Hybrid Friday Lecture Series
(open to the Rockefeller and Tri-Institutional communities)
Friday, September 20, 2024
Venki Ramakrishnan, Ph.D.
MRC Laboratory of Molecular Biology, Cambridge University
Initiation of Translation in Eukaryotes
Recommended Readings:
Brito Querido, Jailson, Irene Díaz-López, and V. Ramakrishnan. “The molecular basis of translation initiation and its regulation in eukaryotes.” Nature Reviews Molecular Cell Biology 25.3 (2024): 168-186.
Brito Querido, Jailson, et al. “The structure of a human translation initiation complex reveals two independent roles for the helicase eIF4A.” Nature Structural & Molecular Biology 31.3 (2024): 455-464.
Wang, Chengyuan, et al. “Structural basis of transcription-translation coupling.” Science 369.6509 (2020): 1359-1365.
Hashem, Yaser, and Joachim Frank. “The jigsaw puzzle of mRNA translation initiation in eukaryotes: a decade of structures unraveling the mechanics of the process.” Annual review of biophysics 47.1 (2018): 125-151.
Aitken, Colin Echeverría, and Jon R. Lorsch. “A mechanistic overview of translation initiation in eukaryotes.” Nature structural & molecular biology 19.6 (2012): 568-576.