Recommended Readings: David Liu, Ph.D., January 19, 2024

Recommended Readings: David Liu, Ph.D., January 19, 2024

Hybrid Friday Lecture Series

(open to the Rockefeller and Tri-Institutional communities)

Friday, January 19, 2024

David Liu, Ph.D.

Professor of Chemistry and Chemical Biology, Harvard University; Investigator, Howard Hughes Medical Institute; Associate Faculty Member, Harvard Microbial Sciences Initiative; Core Institute Member and Vice-Chair of the Faculty, Broad Institute of Harvard and MIT; Director, Chemical Biology and Therapeutics Science (CBTS) Program at the Broad Institute; Richard Merkin Professor and Director of the Merkin Institute of Transformative Technologies in Healthcare at the Broad Institute of Harvard and MIT; Thomas Dudley Cabot Professor of the Natural Sciences, Harvard University

Base Editing and Prime Editing: Engineered Proteins that Precisely Correct Pathogenic Mutations in Cells, Animals, and Patients

Recommended Readings:

Arbab, Mandana, et al. “Base editing rescue of spinal muscular atrophy in cells and in mice.” Science 380.6642 (2023): eadg6518.

Banskota, Samagya, et al. “Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins.” Cell 185.2 (2022): 250-265.

Chen, Peter J., et al. “Enhanced prime editing systems by manipulating cellular determinants of editing outcomes.” Cell 184.22 (2021): 5635-5652.

Newby, Gregory A., et al. “Base editing of haematopoietic stem cells rescues sickle cell disease in mice.” Nature 595.7866 (2021): 295-302.

Blum, Travis R., et al. “Phage-assisted evolution of botulinum neurotoxin proteases with reprogrammed specificity.” Science 371.6531 (2021): 803-810.

By |2024-01-02T21:44:53+00:00January 2nd, 2024|Categories: Friday Lectures, Recommended Readings|Tags: , , |Comments Off on Recommended Readings: David Liu, Ph.D., January 19, 2024

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