Hybrid Monday Lecture Series
(open to the Rockefeller community)
Monday, December 4, 2023
Robert Roeder, Ph.D.
Arnold and Mabel Beckman Professor, Head of the Laboratory of Biochemistry and Microbiology,
The Rockefeller University
Mechanistic Studies of Transcriptional Regulation in Hematopoietic Malignancies
Recommended Readings:
Crump, Nicholas T., et al. “MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia.” Nature Communications 14.1 (2023): 5208.
Malik, Sohail, and Robert G. Roeder. “Regulation of the RNA polymerase II pre-initiation complex by its associated coactivators.” Nature Reviews Genetics 24.11 (2023): 767-782.
Chen, Q. et al. “LYL1 facilitates AETFC assembly and gene activation by recruiting CARM1 in t(8;21) AML.” Proc. Natl. Acad. Sci. U.S.A. 119, e2213718119 (2022).
Ito, K. et al. “Critical roles of transcriptional coactivator MED1 in the formation and function of mouse adipose tissues.” Genes Dev. 35, 729–748 (2021).
Pi, W.C. et al. “E2A-PBX1 functions as a coactivator for RUNX1 in acute lymphoblastic leukemia.” Blood 136, 11–23 (2020).
