Monday Lecture Series
(open to the Rockefeller community)
Monday, May 2, 2022
Ali H. Brivanlou, Ph.D.
Robert and Harriet Heilbrunn Professor,
Head of the Laboratory of Synthetic Embryology,
The Rockefeller University
Synthetic by Design: Weaving Human Embryonic Patterns
Recommended Readings:
Empirical Articles
Piccolo, F. M., Kastan, N. R., Haremaki, T., Tian, Q., Laundos, T. L., De Santis, R., Beaudoin, A. J., Carroll, T. S., Luo, J. D., Gnedeva, K., Etoc, F., Hudspeth, A. J., & Brivanlou, A. H. (2022). Role of YAP in early ectodermal specification and a Huntington’s Disease model of human neurulation. eLife, 11, e73075.
De Santis, R., Etoc, F., Rosado-Olivieri, E. A., & Brivanlou, A. H. (2021). Self-organization of human dorsal-ventral forebrain structures by light induced SHH. Nature communications, 12(1), 6768.
Galgoczi, S., Ruzo, A., Markopoulos, C., Yoney, A., Phan-Everson, T., Li, S., Haremaki, T., Metzger, J. J., Etoc, F., & Brivanlou, A. H. (2021). Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects. Development (Cambridge, England), 148(19), dev199513.
Phan-Everson, T., Etoc, F., Li, S., Khodursky, S., Yoney, A., Brivanlou, A. H., & Siggia, E. D. (2021). Differential compartmentalization of BMP4/NOGGIN requires NOGGIN trans-epithelial transport. Developmental cell, 56(13), 1930–1944.e5.
Yang, M., Rito, T., Metzger, J., Naftaly, J., Soman, R., Hu, J., Albertini, D. F., Barad, D. H., Brivanlou, A. H., & Gleicher, N. (2021). Depletion of aneuploid cells in human embryos and gastruloids. Nature cell biology, 23(4), 314–321.
Review Articles
Rosado-Olivieri, E. A., & Brivanlou, A. H. (2021). Synthetic by design: Exploiting tissue self-organization to explore early human embryology. Developmental biology, 474, 16–21.
