Monday Lectures
Monday, December 11, 2017 3:45 p.m.
Carson Family Auditorium
Thomas Walz, Ph.D.
Professor and Head
Laboratory of Molecular Electron Microscopy
The Rockefeller University
An Experimental Look at Hydrophobic Mismatch
Recommended Readings:
Empirical Articles
Mi, Wei; Li, Yanyan; Yoon, Sung Hwan; et al. (2017). Structural basis of MsbA-mediated lipopolysaccharide transport. NATURE. Volume: 549 (7671): 233-+
Saboe, Patrick O.; Rapisarda, Chiara; Kaptan, Shreyas; et al. (2017). Role of Pore-Lining Residues in Defining the Rate of Water Conduction by Aquaporin-0. BIOPHYSICAL JOURNAL. 112 (5): 953-965
Hite, Richard K.; Yuan, Peng; Li, Zongli; et al. (2015). Cryo-electron microscopy structure of the Slo2.2 Na+-activated K+ channel. NATURE. 527 (7577): 198-+
Shen, Yue-xiao; Si, Wen; Erbakan, Mustafa; et al. (2015). Highly permeable artificial water channels that can self-assemble into two-dimensional arrays. PNAS. 112 (32):9810-9815
Gonen, T; Cheng, YF; Sliz, P; et al. (2005). Lipid-protein interactions in double-layered two-dimensional AQPO crystals. NATURE. 438 (7068): 633-638
Review Paper
Hite, Richard K.; Raunser, Stefan; Walz, Thomas (2007). Revival of electron crystallography. CURRENT OPINION IN STRUCTURAL BIOLOGY. 17 (4): 389-395
Gonen, Tamir; Walz, Thomas (2006). The structure of acquaporins. QUARTERLY REVIEWS OF BIOPHYSICS. 39 (4): 361-396
Book Chapter
Schenk, Andreas D.; Hite, Richard K.; Engel, Andreas; et al. (2010). ELECTRON CRYSTALLOGRAPHY AND AQUAPORINS. METHODS IN ENZYMOLOGY. Book Series: Methods in Enzymology. 483: 91-119
Raunser, Stefan; Walz, Thomas (2009). Electron Crystallography as a Technique to Study the Structure on Membrane Proteins in a Lipidic Environment. ANNUAL REVIEW OF BIOPHYSICS. Book Series: Annual Review of Biophysics. 38: 89-105