Friday Lectures
Friday, April 21, 2017 3:45 p.m.
Caspary Auditorium
Edith Heard, Ph.D.
Professor and Chair, Epigenetics and Cellular Memory, Collège de France
Director, Department of Genetics and Developmental Biology
Institut Curie
The Epigenetic Dynamics of X-chromosome Inactivation: Fine-tuning Gene Dosage during Development
Recommended Readings:
https://www.sciencedaily.com/releases/2017/04/170417114752.htm
da Rocha, Simao T.; Heard, Edith (2017). Novel players in X inactivation: insights into Xist-mediated gene silencing and chromosome conformation. NATURE STRUCTURAL & MOLECULAR BIOLOGY. 24(3): 197-204
Borensztein, Maud; Syx, Laurene; Ancelin, Katia; et al. (2017). Xist-dependent imprinted X inactivation and the early developmental consequences of its failure. NATURE STRUCTURAL & MOLECULAR BIOLOGY. 24(3): 226-+
Giorgetti, Luca; Lajoie, Bryan R.; Carter, Ava C.; et al. (2016). Structural organization of the inactive X chromosome in the mouse. NATURE. 535(7613): 575-+
Wu, Hao; Luo, Junjie; Yu, Huimin; et al. (2014). Cellular Resolution Maps of X Chromosome Inactivation: Implications for Neural Development, Function, and Disease. NEURON. 81(1): 103-119