Friday Lectures
Friday, February 24, 2017 3:45 p.m.
Caspary Auditorium
Jeffrey M. Friedman, M.D., Ph.D.
Marilyn M. Simpson Professor and Head,
Laboratory of Molecular Genetics
The Rockefeller University
Leptin Physiology, Pathophysiology and
the Neural Circuit Regulating Body Weight
Recommended Readings:
Friedman, Jeffrey (2016). The long road to leptin. JOURNAL OF CLINICAL INVESTIGATION. 126(12): 4727-4734
Friedman, Jeffrey M.; Mantzoros, Christos S. (2015). 20 years of leptin: From the discovery of the leptin gene to leptin in our therapeutic armamentarium. METABOLISM-CLINICAL AND EXPERIMENTAL. 64(1): 1-4 PLEASE REQUEST FROM MARKUS LIBRARY
Bouret, Sebastien G.; Bates, Sarah H.; Chen, Stephen; et al. (2012). Distinct Roles for Specific Leptin Receptor Signals in the Development of Hypothalamic Feeding Circuits. JOURNAL OF NEUROSCIENCE. 32(4): 1244-1252
Domingos, Ana I.; Vaynshteyn, Jake; Voss, Henning U.; et al. (2011). Leptin regulates the reward value of nutrient. NATURE NEUROSCIENCE. 14(12): 1562-U92
Davis, Jon F.; Choi, Derrick L.; Schurdak, Jennifer D.; et al. (2011). Leptin Regulates Energy Balance and Motivation Through Action at Distinct Neural Circuits. BIOLOGICAL PSYCHIATRY. 69(7): 668-674
Mantzoros, Christos S.; Magkos, Faidon; Brinkoetter, Mary; et al. (2011). Leptin in human physiology and pathophysiology. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 301(4): E567-E584
Wang, May-yun; Chen, Lijun; Clark, Gregory O.; et al. (2010). Leptin therapy in insulin-deficient type I diabetes. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 107(11): 4813-4819
Oral, EA; Simha, V; Ruiz, E; et al. (2002). Leptin-replacement therapy for lipodystrophy. NEW ENGLAND JOURNAL OF MEDICINE. 346(8): 570-578
