Recommended Readings: Alexander Soukas, M.D., Ph.D.; July 20, 2009

Monday Lecture Series

Genetics of lipid storage: lessons learned from C. elegans

Alexander Soukas, M.D., Ph.D.

Instructor, Dept. of Medicine, Massachusetts General Hospital, Harvard Medical School

Monday, July 20, 2009

4:00 p.m.-5:00 p.m. (Refreshments, 3:45 p.m.)

Second Floor, Welch Hall

Recommended Articles:

Soukas, A. A., E. A. Kane, C. E. Carr, J. A. Melo, and G. Ruvkun. 2009. Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans. Genes and Development. 23(4):496-511.


Greer, E. R., C. L. Pérez, M. R. Van Gilst, B. H. Lee, and K. Ashrafi. 2008. Neural and molecular dissection of a C. elegans sensory circuit that regulates fat and feeding. Cell Metabolism. 8(2):118-131.


Srinivasan, S., L. Sadegh, I. C. Elle, A. G. L. Christensen, N. J. Faergeman, and K. Ashrafi. 2008. Serotonin regulates C. elegans fat and feeding through independent molecular mechanisms. Cell Metabolism. 7(6): 533-544.


Wang, M. C., E. J. O’Rourke, and G. Ruvkun. 2008. Fat metabolism links germline stem cells and longevity in C. elegans. Science. 322(5903):957-960.


Xie, T. 2008. Physiology: Burn fat, live longer. Science. 322(5903):865-866.


Zhang, J., C. Yang, C. Brey, M. Rodriguez, Y. Oksov, R. Gaugler, E. Dickstein, C. -H Huang, and S. Hashmi. 2009. Mutation in Caenorhabditis elegans krüppel-like factor, KLF-3 results in fat accumulation and alters fatty acid composition. Experimental Cell Research (article in Press).