Recommended Readings: Thomas P. Sakmar, M.D., Monday May 22th, 2017

Monday Lectures

Monday, May 22, 2017  3:45 p.m.

Carson Family Auditorium

Thomas P. Sakmar, M.D.

Richard M. and Isabel P. Furlaud Professor and Head,

Laboratory of Chemical Biology and Signal Transduction

The Rockefeller University

Uveal Melanoma: Case History of a Mutant GPCR

Recommended Readings:

https://medicalxpress.com/news/2017-04-newly-chemical-reaction-eye-vision.html

Chua V, Lapadula D, Randolph C, Benovic JL, Wedegaertner PB, Aplin AE. (2017). Dysregulated GPCR Signaling and Therapeutic Options in Uveal Melanoma. MOLECULAR CANCER RESEARCH. 15(5):501-506

Moore, Amanda R.; Ceraudo, Emilie; Sher, Jessica J.; et al. (2016). Recurrent activating mutations of G-protein-coupled receptor CYSLTR2 in uveal melanoma. NATURE GENETICS. 48(6): 675-+

Shoushtari, Alexander N.; Carvajal, Richard D. (2014). GNAQ and GNA11 mutations in uveal melanoma. MELANOMA RESEARCH. 24(6): 525-534. PLEASE REQUEST FROM MARKUS LIBRARY.

Harbour, J. William (2012). The genetics of uveal melanoma: an emerging framework for targeted therapy. PIGMENT CELL & MELANOMA RESEARCH. 25(2)

Periole, Xavier; Knepp, Adam M.; Sakmar, Thomas P.; et al. (2012). Structural Determinants of the Supramolecular Organization of G Protein-Coupled Receptors in Bilayers. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 134(26): 10959-10965