Recommended Readings: Bonnie Bassler, Ph.D.

Friday Lecture Series

Manipulating Quorum Sensing to Control Bacterial Pathogenesis

Bonnie Bassler, Ph.D., Squibb Professor in Molecular Biology and director,

Council on Science and Technology,

Princeton University

October 11, 2013

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Readings

Bassler, B., & Vogel, J. (2013). Bacterial regulatory mechanisms: The gene and beyond. Current Opinion in Microbiology, 16(2), 109-111

Chen, G., Swem, L., Swem, D., Stauff, D., O’Loughlin, C., Jeffrey, P., . . . Hughson, F. (2011). A strategy for antagonizing quorum sensing. Molecular Cell, 42(2), 199-209

Stauff, D. L., & Bassler, B. L. (2011). Quorum sensing in chromobacterium violaceum: DNA recognition and gene regulation by the CviR receptor. Journal of Bacteriology, 193(15), 3871-3878

Swem, L. R., Swem, D. L., O’Loughlin, C. T., Gatmaitan, R., Zhao, B., Ulrich, S. M., & Bassler, B. L. (2009). A quorum-sensing antagonist targets both membrane-bound and cytoplasmic receptors and controls bacterial pathogenicity. Molecular Cell, 35(2), 143-153

Teng, S. -., Schaffer, J. N., Tu, K. C., Mehta, P., Lu, W., Ong, N. P., . . . Wingreen, N. S. (2011). Active regulation of receptor ratios controls integration of quorum-sensing signals in vibrio harveyi. Molecular Systems Biology, 7

 

Recommended Readings: Bonnie Bassler, Ph.D.; April 3, 2009

Friday Lecture Series

“Eavesdropping on Bacterial Conversations”

Wiley Prize in Biomedical Sciences

Bonnie Bassler, Ph.D.

Squibb Professor, Department of Molecular Biology, Princeton University and Investigator, Howard Hughes Medical Institute

April 3, 2009

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Articles:

Hammer, B. K., and B. L. Bassler. 2009. Distinct sensory pathways in Vibrio cholerae El Tor and classical biotypes modulate cyclic dimeric GMP levels to control biofilm formation. Journal of Bacteriology. 91(1): 169-177.

 

Hammer, B.K., Bassler, B.L. 2007. Regulatory small RNAs circumvent the conventional quorum sensing pathway in pandemic Vibrio cholerae. Proceedings of the National Academy of Sciences of the United States of America. 104(27): 11145-11149.

 

Higgins, D. A., M. E. Pomianek, C. M. Kraml, R. K. Taylor, M. F. Semmelhack, and B. L. Bassler. 2007. The major Vibrio cholerae autoinducer and its role in virulence factor production. Nature. 450 (7171): 883-886.

 

Neiditch, M. B., M. J. Federle, A. J. Pompeani, R. C. Kelly, D. L. Swem, P. D. Jeffrey, B. L. Bassler, and F. M. Hughson. 2006. Ligand-induced asymmetry in histidine sensor kinase complex regulates quorum sensing. Cell. 126 (6): 1095-1108.

 

Svenningsen, S. L., K. C. Tu, and B. L. Bassler. 2009. Gene dosage compensation calibrates four regulatory RNAs to control Vibrio cholerae quorum sensing. EMBO Journal. 28 (4): 429-439.

 

Waters, C. M., and B. L. Bassler. 2006. The Vibrio harveyi quorum-sensing system uses shared regulatory components to discriminate between multiple autoinducers. Genes and Development. 20(19): 2754-2767.

 

Waters, C. M., W. Lu, J. D. Rabinowitz, and B. L. Bassler. 2008. Quorum sensing controls biofilm formation in Vibrio cholerae through modulation of cyclic di-GMP levels and repression of vpsT. Journal of Bacteriology. 190(7): 2527-2536.