Recommended Readings: Ronald Breaker, Ph.D., May 1

Friday Lecture Series
Friday, May 1, 2015
3:45 p.m., Caspary Auditorium

Ronald Breaker, Ph.D.
Henry Ford II Professor,
Professor, Molecular Biophysics and Biochemistry,
Yale University
Investigator, Howard Hughes Medical Institute

Prospects for Riboswitch and Ribozyme Discovery

Empirical Articles

Baker, J. L., Sudarsan, N., Weinberg, Z., Roth, A., Stockbridge, R. B., & Breaker, R. R. (2012). Widespread genetic switches and toxicity resistance proteins for fluoride. Science, 335(6065), 233-235. doi:10.1126/science.1215063

Kim, P. B., Nelson, J. W., & Breaker, R. R. (2015). An ancient riboswitch class in bacteria regulates purine biosynthesis and one-carbon metabolism. Molecular Cell, 57(2), 317-328. doi:10.1016/j.molcel.2015.01.001

Nelson, J. W., Sudarsan, N., Furukawa, K., Weinberg, Z., Wang, J. X., & Breaker, R. R. (2013). Riboswitches in eubacteria sense the second messenger c-di-AMP. Nature Chemical Biology, 9(12), 834-839. doi:10.1038/nchembio.1363

Roth, A., Weinberg, Z., Chen, A. G., Kim, P. B., Ames, T. D., & Breaker, R. R. (2014). A widespread self-cleaving ribozyme class is revealed by bioinformatics. Nature chemical biology, 10(1), 56-60. doi:10.1038/nchembio.1386

Review Papers

Breaker, R. R. (2012). Riboswitches and the RNA world. Cold Spring Harbor Perspectives in Biology, 4(2), a003566. doi:10.1101/cshperspect.a003566

Breaker, R. R., & Joyce, G. F. (2014). The expanding view of RNA and DNA function. Chemistry & Biology, 21(9), 1059-1065. doi:10.1016/j.chembiol.2014.07.008