Recommended Readings: Michael P. Rout, Ph.D., Monday May 15th, 2017

Monday Lectures

Monday, May 15, 2017  3:45 p.m.

Carson Family Auditorium

Michael P. Rout, Ph.D.

 Professor and Head,

Laboratory of Cellular and Structural Biology

The Rockefeller University

Getting the Hole Picture: Structure-Function Mapping of the Nuclear Pore Complex

Recommended Readings:

http://www.the-scientist.com/?articles.view/articleNo/47529/title/Nuclear-Pores-Come-into-Sharper-Focus/

Timney, Benjamin L.; Raveh, Barak; Mironska, Roxana; et al. (2016). Simple rules for passive diffusion through the nuclear pore complex. JOURNAL OF CELL BIOLOGY. 215(1): 57-76

Raveh, Barak; Karp, Jerome M.; Sparks, Samuel; et al. (2016). Slide-and-exchange mechanism for rapid and selective transport through the nuclear pore complex. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA . 113(18): E2489-E2497

Fernandez-Martinez, Javier; Kim, Seung Joong; Shi, Yi; et al. (2016). Structure and Function of the Nuclear Pore Complex Cytoplasmic mRNA Export Platform. CELL. 167(5): 1215-+

Tu, Li-Chun; Fu, Guo; Zilman, Anton; et al. (2013). Large cargo transport by nuclear pores: implications for the spatial organization of FG-nucleoporins.EMBO JOURNAL. 32(24): 3220-3230

Fernandez-Martinez, Javier; Phillips, Jeremy; Sekedat, Matthew D.; et al. (2012). Structure-function mapping of a heptameric module in the nuclear pore complex. JOURNAL OF CELL BIOLOGY. 196(4): 419-434

Grossman, Einat; Medalia, Ohad; Zwerger, Monika (2012). Functional Architecture of the Nuclear Pore Complex. ANNUAL REVIEW OF BIOPHYSICS. 41: 557-584

Recommended Readings: Michael P Rout PhD Monday Oct 17, 2011

Monday Lecture Series

The Architecture and Transport Mechanism of the Nuclear Pore Complex

Michael P. Rout  Ph.D. 

Laboratory of Cellular and Structural Biology

The Rockefeller University

October 17,  2011

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

 

Recommended Readings:

Sampathkumar P; Gheyi T; Miller SA; et al.  2011.  Structure of the C-terminal domain of Saccharomyces cerevisiae Nup133, a component of the nuclear pore complex.   Proteins-Structure Function and Bioinformatics,  79(5):1672-1677.      Request from Markus Library .

Cohem S; Au S; Pante, N.  2011.  How viruses access the nucleus.  Biochimica et Biophysica Acta – Molecular Cell Research,  1813(9; Spcl Iss. 1):1634-1645.

Hoelz, A; Debler EW; Blobel G. 2011.  The Structure of the nuclear pore complex.   Annual Review of Biochemistry,   80:613-643.

Strambio-de-Castillia C; Niepel M; Rout MP.  2010.  The nuclear pore complex: bridging nuclear transport and gene regulation.   Nature Reviews Molecular Biology,  11(7):490-501.

Wente SR; Rout MP.  2010.  The nuclear pore comlex and nuclear transport.   Cold Spring Harbor Perspectives in Biology,  2(10):a000562

Cook, A; Bono F; Jinek M; et al.   2007.  Structural biology of nucleocytoplasmic transport.   Annual Review of Biochemistry, 76:647-671.

D’Angelo MA; Hetzer MW.   2008.  Structure, dynamics and function of nuclear pore complexes.  Trends in Cell Biology, 18(10):456-466.

Recommended Readings: Andre Hoelz, Ph.D.; May 13, 2009

Special Seminar Series

            “Building the Gatekeeper of the Innermost Sanctuary of the Cell Piece by Piece”

Andre Hoelz, Ph.D.

Research Associate, Laboratory of Cell Biology

The Rockefeller University

Wednesday, May 13, 2009

4:00 p.m.-5:00 p.m. (Refreshments, 3:45 p.m.)

Second Floor, Welch Hall

Recommended Articles:

Debler, E. W., Y. Ma, H. -S Seo, K. -C Hsia, T. R. Noriega, G. Blobel, and A. Hoelz. 2008. A fence-like coat for the nuclear pore membrane. Molecular cell. 32(6):815-826.

Hoelz, A., and G. Blobel. 2004. Popping out of the nucleus. Nature. 432(7019):815-816.

Hsia, K. -C, P. Stavropoulos, G. Blobel, and A. Hoelz. 2007. Architecture of a coat for the nuclear pore membrane. Cell. 131(7):1313-1326.

Melcak, I., A. Hoelz, and G. Blobel. 2007. Structure of Nup58/45 suggests flexible nuclear pore diameter by intermolecular sliding. Science. 315(5819):1729-1732.

Napetschnig, J., G. Blobel, and A. Hoelz. 2007. Crystal structure of the N-terminal domain of the human protooncogene Nup214/CAN. Proceedings of the National Academy of Sciences of the United States of America. 104(6):1783-1788.

Stavropoulos, P., V. Nagy, G. Blobel, and A. Hoelz. 2008. Molecular basis for the autoregulation of the protein acetyl transferase Rtt109. Proceedings of the National Academy of Sciences of the United States of America. 105(34):12236-12241.