Scripps Scientists Solve Long-Standing Mystery of Protein “Quality Control” Mechanism

Scientists from The Scripps Research Institute have solved a long-standing mystery of how cells conduct “quality control” to eliminate the toxic effects of a certain kind of error in protein production. The findings may lead to a better understanding of a host of neurodegenerative diseases.  The new study, published by NATURE online recently,  suggests how cells in eukaryotic organisms, like humans, sense and destroy “non-stop” proteins that remain stuck in the ribosome, the protein manufacturing plant of the cell.