Recommended Readings: Nicolas Tritsch, Ph.D., January 28

Special Lecture Series
Wednesday, January 28, 2015
4:00 p.m., Carson Family Auditorium (CRC)

Nicolas Tritsch, Ph.D.
Postdoctoral Fellow,
Department of Neurobiology,
Harvard Medical School

Lost in Translation – What do Dopamine Neurons Tell the Brain?

Recommended Readings

Empirical Articles

Straub, C., Tritsch, N. X., Hagan, N. A., Gu, C., & Sabatini, B. L. (2014). Multiphasic modulation of cholinergic interneurons by nigrostriatal afferents. The Journal of Neuroscience, 34(25), 8557–8569. doi:10.1523/JNEUROSCI.0589-14.2014

Tritsch, N., Oh, W., Gu, C., & Sabatini, B. (2014). Midbrain dopamine neurons sustain inhibitory transmission using plasma membrane uptake of GABA, not synthesis. eLife. doi:10.7554/eLife.01936

Tritsch, N. X., Ding, J. B., & Sabatini, B. L. (2012). Dopaminergic neurons inhibit striatal output through non-canonical release of GABA. Nature, 490(7419), 262–266. doi:10.1038/nature11466

Review Papers

Tritsch, N. X., & Sabatini, B. L. (2012). Dopaminergic modulation of synaptic transmission in cortex and striatum. Neuron, 76(1), 33–50. doi:10.1016/j.neuron.2012.09.023

Recommended Readings: Timothy Ryan, Ph.D. December 8

Monday Lecture Series
Monday, December 8, 2014,
4:00 p.m., Carson Family Auditorium (CRC)

Timothy Ryan, Ph.D.
Tri-Institutional Professor,
Department of Biochemistry,
Weill Cornell Medical College

How Synapses Regulate Their Diet: the Balance of Fuel Production and Expenditure and Single Synapses

Recommended Readings

Empirical Articles

Cottrell, J. R., Levenson, J. M., Kim, S. H., Gibson, H. E., Richardson, K. a, Sivula, M., … Gerber, D. J. (2013). Working memory impairment in calcineurin knock-out mice is associated with alterations in synaptic vesicle cycling and disruption of high-frequency synaptic and network activity in prefrontal cortex. The Journal of Neuroscience, 33(27), 10938–10949. doi:10.1523/JNEUROSCI.5362-12.2013

Fernandez-Alfonso, T., & Ryan, T. A. (2008). A heterogeneous “resting” pool of synaptic vesicles that is dynamically interchanged across boutons in mammalian CNS synapses. Brain Cell Biology, 36(1-4), 87–100. doi:10.1007/s11068-008-9030-y

Kim, S. H., & Ryan, T. A. (2010). CDK5 serves as a major control point in neurotransmitter release. Neuron, 67(5), 797–809. doi:10.1016/j.neuron.2010.08.003

Rangaraju, V., Calloway, N., & Ryan, T. A. (2014). Activity-driven local ATP synthesis is required for synaptic function. Cell, 156(4), 825–835. doi:10.1016/j.cell.2013.12.042

Review Paper

Dittman, J., & Ryan, T. a. (2009). Molecular circuitry of endocytosis at nerve terminals. Annual Review of Cell and Developmental Biology, 25, 133–160. doi:10.1146/annurev.cellbio.042308.113302

Recommended Readings: Erin Schuman, Ph.D.

Friday Lecture Series

Transcriptomes and Proteomes at Synapses

Erin Schuman, Ph.D., director, department of synaptic plasticity, and professor,

Max Planck Institute for Brain Research

 March 22, 2012

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Readings

Bingol, B., & Schuman, E. M. (2005). Synaptic protein degradation by the ubiquitin proteasome system. Current Opinion in Neurobiology, 15(5), 536-541

Sutton, M. A., & Schuman, E. M. (2006). Dendritic protein synthesis, synaptic plasticity, and memory. Cell, 127(1), 49-58

Sutton, M. A., & Schuman, E. M. (2005). Local translational control in dendrites and its role in long-term synaptic plasticity. Journal of Neurobiology, 64(1), 116-131

Sutton, M. A., & Schuman, E. M. (2009). Partitioning the synaptic landscape: Distinct microdomains for spontaneous and spike-triggered neurotransmission. Science Signaling, 2(65)

Tai, H. -., & Schuman, E. M. (2008). Ubiquitin, the proteasome and protein degradation in neuronal function and dysfunction. Nature Reviews Neuroscience, 9(11), 826-838