Recommended Readings: Charles D. Gilbert, M.D., Ph.D. December 15

Monday Lecture Series
Monday, December 15, 2014
4:00 p.m., Carson Family Auditorium

Charles D. Gilbert, M.D., Ph.D.
Arthur and Janet Ross Professor and Head,
Laboratory of Neurobiology,
The Rockefeller University

The Dynamic Brain

Recommended Readings

Empirical Articles

Piëch, V., & Li, W., & Gilbert, C. D. (2013). Network model of top-down influences on local gain and contextual interactions in visual cortex. Proceedings of the National Academy of Sciences. 110(43), E4108-E4117. doi:10.1073/pnas.1317019110

Ramalingam, N., McManus, J. N. J., Li, W., & Gilbert, C. D. (2013). Top-down modulation of lateral interactions in visual cortex. The Journal of Neuroscience, 33(5), 1773–1789. doi:10.1523/JNEUROSCI.3825-12.2013

Yamahachi, H., Marik, S., McManus, J., Denk, W., & Gilbert, C. D. (2009). Rapid axonal sprouting and pruning accompany functional reorganization in primary visual cortex. Neuron, 64(5), 719-729. doi:10.1016/j.neuron.2009.11.026

Review Papers

Gilbert, C. D., & Li, W. (2013). Top-down influences on visual processing. Nature Reviews Neuroscience, 14(5), 350–363. doi:10.1038/nrn3476

Gilbert, C., & Li, W. (2012). Adult visual cortical plasticity. Neuron, 75(2), 250–264. doi:10.1016/j.neuron.2012.06.030

Recommended Readings: Ali H. Brivanlou, Ph.D. November 24

Monday Lecture Series
Monday, November 24, 2014
4:00 p.m., Carson Family Auditorium

Ali H. Brivanlou, Ph.D.
Robert and Harriet Heilbrunn Professor and Head,
Laboratory of Stem Cell Biology and Molecular Embryology,
The Rockefeller University

Dynamic Patterns: Self-Organization of Human Embryonic Cells

Recommended Readings

Empirical Articles

Arduini, B., & Brivanlou, A. (2012). Modulation of FOXD3 activity in human embryonic stem cells directs pluripotency and paraxial mesoderm fates. Stem Cells, 30(10), 2188–2198. doi:10.1002/stem.2012

Ozair, M., Noggle, S., & Warmflash, A. (2013). SMAD7 directly converts human embryonic stem cells to telencephalic fate by a default mechanism. Stem Cells, 31(1), 35–47. doi:10.1002/stem.1246.SMAD7

Rosa, A., Papaioannou, M. D., Krzyspiak, J. E., & Brivanlou, A. H. (2014). miR-373 is regulated by TGFβ signaling and promotes mesendoderm differentiation in human embryonic stem cells. Developmental Biology, 391(1), 81–88. doi:10.1016/j.ydbio.2014.03.020

Warmflash, A., Sorre, B., Etoc, F., Siggia, E. D., & Brivanlou, A. H. (2014). A method to recapitulate early embryonic spatial patterning in human embryonic stem cells. Nature Methods, 11(8). doi:10.1038/nmeth.3016

Review Article

Muñoz-Sanjuán, I., & Brivanlou, A. H. (2002). Neural induction, the default model, and embryonic stem cells. Nature Reviews Neuroscience, 3(4), 271–280. doi:10.1038/nrn786

Was the Cerebellum the Center of Evolutionary Change That Makes Us Human?

When we search for the seat of humanity, are we looking at the wrong part of the brain? Most neuroscientists assume that the neocortex, the brain’s distinctive folded outer layer, is the thing that makes us uniquely human. But a new study suggests that another part of the brain, the cerebellum, grew much faster in our ape ancestors.

Read more on this new research in Current Biology.

 

Recommended Readings: Madeline Lancaster, Ph.D. Monday, Dec. 11

Special Lecture
The Human Brain in a Dish: Using Cerebral Organoids to Model Development and Disease
Madeline A. Lancaster, Ph.D.
Postdoctoral Fellow
Institute of Molecular Biotechnology
4:00 p.m., Carson Family Auditorium

Recommended Readings

Review Papers

Eiraku, M., & Sasai, Y. (2012). Self-formation of layered neural structures in three-dimensional culture of ES cells. Current Opinion in Neurobiology, 22(5), 768–777. doi:10.1016/j.conb.2012.02.005

Gage, F. H., & Temple, S. (2013). Neural stem cells: generating and regenerating the brain. Neuron, 80(3), 588–601. doi:10.1016/j.neuron.2013.10.037

Han, S. S. W., Williams, L. a, & Eggan, K. C. (2011). Constructing and deconstructing stem cell models of neurological disease. Neuron, 70(4), 626–644. doi:10.1016/j.neuron.2011.05.003

Lui, J. H., Hansen, D. V, & Kriegstein, A. R. (2011). Development and evolution of the human neocortex. Cell, 146(1), 18–36. doi:10.1016/j.cell.2011.06.030

Empirical Articles

Espuny-Camacho, I., Michelsen, K. a, Gall, D., Linaro, D., Hasche, A., Bonnefont, J., … Vanderhaeghen, P. (2013). Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo. Neuron, 77(3), 440–456. doi:10.1016/j.neuron.2012.12.011

Lancaster, M. a, Renner, M., Martin, C.-A., Wenzel, D., Bicknell, L. S., Hurles, M. E., … Knoblich, J. a. (2013). Cerebral organoids model human brain development and microcephaly. Nature, 501(7467), 373–379. doi:10.1038/nature12517

Mariani, J., Simonini, M. V., Palejev, D., Tomasini, L., Coppola, G., Szekely, A. M., … Vaccarino, F. M. (2012). Modeling human cortical development in vitro using induced pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America, 109(31), 12770–12775. doi:10.1073/pnas.1202944109