Recommended Readings: Xiaowei Zhuang, Ph.D. October 16

Harvey Society Lecture Series
Thursday, October 16, 2014
8:00 p.m., Caspary Auditorium

Xiaowei Zhuang, Ph.D.
Professor of Chemistry and Chemical Biology
Professor of Physics,
Harvard University
Howard Hughes Medical Institute

Illuminating Biology at the Nanoscale with Single-Molecule and Super-Resolution Fluorescence Microscopy

Recommended Readings

Empirical Articles

Bates, M., Huang, B., Dempsey, G. T., & Zhuang, X. (2007). Multicolor super-resolution imaging with photo-switchable fluorescent probes. Science, 317(5845), 1749–1753. doi:10.1126/science.1146598

Huang, B., Wang, W., Bates, M., & Zhuang, X. (2008). Three-dimensional super-resolution imaging by stochastic optical reconstruction microscopy. Science, 319(5864), 810–813. doi:10.1126/science.1153529

Xu, K., Babcock, H. P., & Zhuang, X. (2012). Dual-objective STORM reveals three-dimensional filament organization in the actin cytoskeleton. Nature Methods, 9(2), 185–188. doi:10.1038/nmeth.1841

Xu, K., Zhong, G., & Zhuang, X. (2013). Actin, spectrin, and associated proteins form a periodic cytoskeletal structure in axons. Science, 339(6118), 452–456. doi:10.1126/science.1232251

Review Papers

Alivisatos, a P., Andrews, A. M., Boyden, E. S., Chun, M., Church, G. M., Deisseroth, K., … Zhuang, X. (2013). Nanotools for neuroscience and brain activity mapping. ACS Nano, 7(3), 1850–1866. doi:10.1021/nn4012847

Huang, B., Babcock, H., & Zhuang, X. (2010). Breaking the diffraction barrier: super-resolution imaging of cells. Cell, 143(7), 1047–1058. doi:10.1016/j.cell.2010.12.002

Recommended Readings: Sangeeta Bhatia, M.D., Ph.D. May 12

Monday, May 12, 2014
4:00 p.m., Carson Family Auditorium

Sangeeta Bhatia, M.D., Ph.D.
John J. and Dorothy Wilson Professor of Health Sciences & Technology
Institute for Medical Engineering and Science
Director, Laboratory for Multiscale Regenerative Technologies
Massachusetts Institute of Technology
Investigator, Howard Hughes Medical Institute

Tiny Technologies for Studying Tissue Microenvironments

Recommended Readings:

Empirical Papers

Chen, A., & Thomas, D. (2011). Humanized mice with ectopic artificial liver tissues. Proceedings of the National Academy of Sciences, 108(29), 11842–11847. doi:10.1073/pnas.1101791108

Hui, E. E., & Bhatia, S. N. (2007). Micromechanical control of cell-cell interactions. Proceedings of the National Academy of Sciences, 104(14), 5722–5726. doi:10.1073/pnas.0608660104

Khetani, S. R., & Bhatia, S. N. (2008). Microscale culture of human liver cells for drug development. Nature Biotechnology, 26(1), 120–126. doi:10.1038/nbt1361

Review Papers

Underhill, G. H., Galie, P., Chen, C. S., & Bhatia, S. N. (2012). Bioengineering methods for analysis of cells in vitro. Annual Review of Cell and Developmental Biology, 28, 385–410. doi:10.1146/annurev-cellbio-101011-155709

Wong, I. Y., Bhatia, S. N., & Toner, M. (2013). Nanotechnology: emerging tools for biology and medicine. Genes & Development, 27(22), 2397–2408. doi:10.1101/gad.226837.113