Recommended Readings: John Mekalanos, Ph.D. October 10

Friday Lecture Series
Friday, October 10, 2014
3:45 p.m., Caspary Auditorium

John Mekalanos, Ph.D.
Adele H. Lehman Professor of Microbiology
Chair, Department of Microbiology and Immunobiology,
Harvard Medical School

The Ghost in the Machine: Understanding Bacterial Secretion Systems Through Defining Their Effectors

Recommended Readings

Empirical Articles

Basler, M., Ho, B. T., & Mekalanos, J. J. (2013). Tit-for-tat: type VI secretion system counterattack during bacterial cell-cell interactions. Cell, 152(4), 884–894. doi:10.1016/j.cell.2013.01.042

Basler, M., Pilhofer, M., Henderson, G. P., Jensen, G. J., & Mekalanos, J. J. (2012). Type VI secretion requires a dynamic contractile phage tail-like structure. Nature, 483(7388), 182–186. doi:10.1038/nature10846

Ma, A. T., McAuley, S., Pukatzki, S., & Mekalanos, J. J. (2009). Translocation of a Vibrio cholerae type VI secretion effector requires bacterial endocytosis by host cells. Cell Host & Microbe, 5(3), 234–243. doi:10.1016/j.chom.2009.02.005

Ma, A. T., & Mekalanos, J. J. (2010). In vivo actin cross-linking induced by Vibrio cholerae type VI secretion system is associated with intestinal inflammation. Proceedings of the National Academy of Sciences, 107(9), 4365–4370. doi:10.1073/pnas.0915156107

Review Papers

Ho, B. T., Dong, T. G., & Mekalanos, J. J. (2014). A view to a kill: the bacterial type VI secretion system. Cell Host & Microbe, 15(1), 9–21. doi:10.1016/j.chom.2013.11.008