Faculty Candidate Seminar
Genome-wide Translational Profiling by Ribosome Footprinting
Nicholas Ingolia, PH.D.
Postdoctoral Fellow, Dept. of Cellular and Molecular Pharmacology, University of California, San Francisco
January 4, 2010
4:00 p.m. Welch Hall, Level Two
Recommended Readings:
Morris DR. 2009. Ribosomal footprints on a transcriptome landscape. GENOME BIOLOGY 10(4):article Number: 215
Bailey-Serres J., Sorenson R., Juntawong P. 2009. Getting the message across: cytoplasmic ribonucleoprotein complexes. TRENDS IN PLANT SCIENCE 14(8): 443-453
Sanz E, Yang L, Su T, Morris DR, McKnight GS, Amieux PS. 2009. Cell-type-specific isolation of ribosome-associated mRNA from complex tissues. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106(33): 13939-13944
Ingolia NT, Ghaemmaghami S, Newman JRS, et al. 2009. Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling. SCIENCE 324(5924): 218-223
Baek D., Villen J, Shin C, Camargo FD, Gygi SP, Bartel DP. 2008. The impact of microRNAs on protein output. NATURE 455(7209): 64-70
Selbach M, Schwanhausser B, Thierfelder N, Fang Z, Khanin R, Rajewsky N. 2008. Widespread changes in protein synthesis induced by microRNAs NATURE 455(7209): 58-63
Berezikov E., Cuppen E., Plasterk RHA. 2006. Approaches to microRNA discovery. NATURE GENETICS 38(suppl 6): S2-S7
Arava Y, Boas FE, Brown PO, Herschlag D. 2005. Dissecting eukaryotic translation and its control by ribosome density mapping. NUCLEIC ACIDS RESEARCH 33(8): 2421-2432