Recommended Readings: Daniel Mucida, Ph.D., April 15

Friday Lecture Series
Friday, April 15, 2016
3:45 p.m., Caspary Auditorium

Daniel Mucida, Ph.D.
Assistant Professor and Head,
Laboratory of Mucosal Immunology,
The Rockefeller University

Tissue Adaptation: Implications for Immunity and Tolerance

Recommended Readings

Empirical Papers

Gabanyi, I., Muller, P. A., Feighery, L., Oliveira, T. Y., Costa-Pinto, F. A., & Mucida, D. (2016). Neuro-immune interactions drive tissue programming in intestinal macrophages. Cell, 164(3), 378-391. doi: doi: 10.1016/j.cell.2015.12.023.

Muller, P. A., Koscsó, B., Rajani, G. M., Stevanovic, K., Berres, M. L., Hashimoto, D., … & Stanley, E. R. (2014). Crosstalk between muscularis macrophages and enteric neurons regulates gastrointestinal motility. Cell, 158(2), 300-313. doi: 10.1016/j.cell.2014.04.050.

Schreiber, H. A., Loschko, J., Karssemeijer, R. A., Escolano, A., Meredith, M. M., Mucida, D., … & Nussenzweig, M. C. (2013). Intestinal monocytes and macrophages are required for T cell polarization in response to Citrobacter rodentium. The Journal of Experimental Medicine, 210(10), 2025-2039. doi: 10.1084/jem.20130903.

Review Papers

Reis, B. S., & Mucida, D. (2012). The role of the intestinal context in the generation of tolerance and inflammation. Clinical and Developmental Immunology, 157948, doi: 10.1155/2012/157948.

Recommended Readings: Elena Gallo MacFarlane, Ph.D., February 8

Special Seminar
Wednesday, February 8, 2016
4:00 p.m., Carson Family Auditorium (CRC)

Elena Gallo MacFarlane, Ph.D.
Postdoctoral and Research Fellow,
Institute of Genetic Medicine,
Johns Hopkins University School of Medicine

The Vessel Wall as a Paracrine Engine in TGF-Beta-Driven Vasculopathies

Recommended Reading:

Chetaille, P., Preuss, C., Burkhard, S., Côté, J. M., Houde, C., Castilloux, J., … & Thibeault, M. (2014). Mutations in SGOL1 cause a novel cohesinopathy affecting heart and gut rhythm. Nature Genetics, 46(11), 1245-1249. doi: 10.1038/ng.3113.

Gallo, E. M., Loch, D. C., Habashi, J. P., Calderon, J. F., Chen, Y., Bedja, D., … & Judge, D. P. (2014). Angiotensin II–dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis. The Journal of Clinical Investigation, 124(1), 448-460. doi: 10.1172/JCI69666.

Gerber, E. E., Gallo, E. M., Fontana, S. C., Davis, E. C., Wigley, F. M., Huso, D. L., & Dietz, H. C. (2013). Integrin-modulating therapy prevents fibrosis and autoimmunity in mouse models of scleroderma. Nature, 503(7474), 126-130. doi: 10.1038/nature12614.

Lindsay, M. E., Schepers, D., Bolar, N. A., Doyle, J. J., Gallo, E., Fert-Bober, J., … & Bjeda, D. (2012). Loss-of-function mutations in TGFB2 cause a syndromic presentation of thoracic aortic aneurysm. Nature Genetics, 44(8), 922-927. doi: 10.1038/ng.2349

Recommended Readings: Jean-Laurent Casanova, Ph.D. December 1

Monday Lecture Series
Monday, December 1, 2014,
4:00 p.m., Carson Family Auditorium (CRC)

Jean-Laurent Casanova, Ph.D.,
Professor and Head,
St. Giles Laboratory of Human Genetics of Infectious Diseases,
The Rockefeller University
Howard Hughes Medical Institute

Toward a Genetic Theory of Childhood Infectious Diseases

Recommended Readings

Empirical Articles

Puel, A., Cypowyj, S., Bustamante, J., Wright, J. F., Liu, L., Lim, H. K., … Casanova, J.-L. (2011). Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. Science, 332(6025), 65–68. doi:10.1126/science.1200439

Sabri, A., Grant, A. V, Cosker, K., El Azbaoui, S., Abid, A., Abderrahmani Rhorfi, I., … El Baghdadi, J. (2014). Association study of genes controlling IL-12-dependent IFN-γ immunity: STAT4 alleles increase risk of pulmonary tuberculosis in Morocco. The Journal of Infectious Diseases, 210(4), 611–618. doi:10.1093/infdis/jiu140

Review Papers

Alcaïs, A., Quintana-Murci, L., Thaler, D. S., Schurr, E., Abel, L., & Casanova, J.-L. (2010). Life-threatening infectious diseases of childhood: single-gene inborn errors of immunity? Annals of the New York Academy of Sciences, 1214, 18–33. doi:10.1111/j.1749-6632.2010.05834.x

Casanova, J.-L., & Abel, L. (2005). Inborn errors of immunity to infection: the rule rather than the exception. The Journal of Experimental Medicine, 202(2), 197–201. doi:10.1084/jem.20050854

Recommended Readings: Mark M. Davis, Ph.D. April 25

Friday Lecture Series
Friday, April 25, 2014
3:45 p.m., Caspary Auditorium

Mark M. Davis, Ph.D.
Burt and Marion Avery Family Professor of Immunology
Director, Stanford Institute for Immunity, Transplantation and Infection
Member, Bio-X and Stanford Cancer Institute
Stanford University

Reinventing Human Immunology

Recommended Readings:

Davis, M. M. (2008). A prescription for human immunology. Immunity, 29(6), 835–838. doi:10.1016/j.immuni.2008.12.003

Davis, M. M. (2012). Immunology taught by humans. Science Translational Medicine, 4(117), 117fs2. doi:10.1126/scitranslmed.3003385

Kidd, B. a, Peters, L. a, Schadt, E. E., & Dudley, J. T. (2014). Unifying immunology with informatics and multiscale biology. Nature Immunology, 15(2), 118–127. doi:10.1038/ni.2787

Maecker, H. T., McCoy, J. P., & Nussenblatt, R. (2012). Standardizing immunophenotyping for the Human Immunology Project. Nature Reviews Immunology, 12(3), 191–200. doi:10.1038/nri3158

Su, L. F., Han, A., McGuire, H. M., Furman, D., Newell, E. W., & Davis, M. M. (2014). The Promised Land of Human Immunology. Cold Spring Harbor Symposia on Quantitative Biology. doi:10.1101/sqb.2013.78.022905