Recommended Readings: Yanick Crow, PhD September 17, 2012

Human Type I Interferonopathies

Yanick Crow  PhD

Professor of Genetic Medicine

University of Manchester, UK

Monday, September 17,  2012

4 p.m. , Caspary Auditorium.   Refreshments 3:45 p.m.

Recommended Review:

Banchereau, J; Pascual, V.  2006.  Type I interferon in systemic lupus erythematosus and other autoimmune diseases.   IMMUNITY.   25( 3):383-392.      DOI: 10.1016/j.immuni.2006.08.010

Recommended Readings:

Crow, Y.  2011.  Type I interferonopathies: a novel set of inborn errors of immunity.  Annals of the New York Academy of Sciences   1238: 91-98.     DOI: 10.1111/j.1749-6632.2011.06220.x

Briggs, Tracy A.; Rice, Gillian I.; Daly, Sarah; et al.   2011. Tartrate-resistant acid phosphatase deficiency causes a bone dysplasia with autoimmunity and a type I interferon expression signature. NATURE GENETICS  43(2):127-U71.     DOI: 10.1038/ng.748


Alcais, A; Quintana-Murci, L; Thaler, DS.; et al.  2010.  Life-threatening infectious diseases of childhood: single-gene inborn errors of immunity?  Annals of the New York Academy of Sciences    1214:18-33.     DOI: 10.1111/j.1749-6632.2010.05834.x

Crow, Yanick J. 2011. Lupus: How much “complexity” is really (just) genetic heterogeneity?  ARTHRITIS AND RHEUMATISM.   63(12): 3661-3664    DOI: 10.1002/art.30603


Crow, Y.; Rehwinkel, J.  2009.  Aicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunity.  HUMAN MOLECULAR GENETICS  18: R130-R136.    DOI: 10.1093/hmg/ddp293

Baechler, EC; Batliwalla, FM; Karypis, G; et al. 2003.  Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus.  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA   100( 5):2610-2615.   DOI: 10.1073/pnas.0337679100



Related Readings: Alexander Tarakhovsky M.D., Ph.D.

Monday Seminar Series

 Chromatin Control of Antiviral response

Alexander Tarakhovsky M.D., Ph.D.

 Irene Diamond Professor of Immunology
The Rockefeller University

 Monday, November 17, 2008

Welch Hall Level Two  Refreshments  3:45   Lecture  4:00

Review article:

Loo, YM and M. Gale.  2007.  Viral regulation and evasion of the host response. Interferon: the 50th anniversary.  Current Topics in microbiology and immunology.  316: 295-313.

Related articles:

Savarin, C. and CC Bergman.  2008.  Neuroimmunology of central nervous system viral infections: the cells, molecules and mechanisms involved.  Current opinion in pharmacology. 8(4)472-479

Su, XW et. al.  2008  Association of single nucelotide ploymorphisms in interferon signaling pathway genes and interferon-stimulated genes with the reponse to interferon therapy for chronic hepatitis C.  Journal of hepatology. 49(2):184-191

Spensberger, D. and R. Delwel.  2008.  A novel interation between the proto-oncogene Evi1 and histone methytransferases, SUV29H1 and G9a.  FEBS Letters.  582(18):2761-2767

Lenschow, DJ et al. 2007.  IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis virusesPNAS 104(4):1371-1376

Avitsur, R.; J. Hunzeker and JF SHeridan.  2006.  Role of early stress in the individual differences in host response to viral infection.  Brain, behavior and immunity. 20(4):339-348