NCI Awards $9.6M for Research into Therapy-Resistant Prostate Cancer

The National Cancer Institute has awarded a five-year, $9.6 million grant to a multidisciplinary team of researchers who will study the molecular underpinnings of prostate cancers that progress to a therapy-resistant state.

The funding is for three projects. One will be directed at determining how hypoxic signals affect gene expression. Another will create new transgenic mouse models to better understand how kinases cooperate “to drive tumorigenesis.” The third project will focus on how microRNAs regulate cell proliferation and prostate cancer progression.