Deep Comparison Reveals Similarities Between Pluripotent and Embryonic Stem Cells

Researchers at the University of Wisconsin, using a combination of techiques, conducted a rigorous analysis of  ESC’s and iPSC’s revealing significant and functionally related differences.   Their research also resulted in the establishment of a new online resource named SCOR for storing and searching data on pluripotency.   Read more in NATURE METHODS. 

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Related Readings: Ali H. Brivanlou PhD

 Monday Seminar Series

 Genetic Dissection of Pluripotency in

Human Embryonic Stem Cells

Ali H. Brivanlou  PhD

Robert and Harriet Heilbrunn Professor 

The Rockefeller University

 Monday, November 3, 2008

Welch Hall Level Two  Refreshments  3:45   Lecture  4:00

Related readings:

Noggle, SA; D. James and AH Brivanlou.  2005.   A molecular basis for human embryonic stem cell pluripotency.  Stem cell reviews.  1(2):111-118.

Schwartz, PH et al.  2008.  Differentiation of neural lineage cells from human pluripotent stem cells. Methods. 45(2):142-158

Stewart, MH; SC BEndell and M. Bhatia.  2008.  Deconstructing human embryonic stem cell cultures: niche regulation of self-renewal and pluripotency.  Journal of molecular medicine.  86(8):875-886

Todeur, S. et al.  2008.  Biology and potentialities of of human embryonic stem cells.  Annales de biologie clinique. 66(3):241-247

Ohtsuka, S. and S. Dalton.  2008.  Molecular and biolgoical properties of pluripotent embryonic stem cells. Gene therapy.  15(2):74-81

Oliveri, RS.  2007.  Epigenetic dedifferentiation of somatic cells into pluripotency: cellular alchemy in the age of regenerative medicine?  Regenerative medicine.  2(5):795-816

Darr, H. and N. Benvenisry.  2006.  Human embryonic stem cells: the battle between self-renewal and differentiation.  Regenerative medicine.  1(3):327-325

Avery, S.; K. Inniss and H. Moore. 2006.  The regulation of self-renewal in human embryonic stem cells.  Stem cells and development.  15(5):729-740.

Skottman, H.; MS Dilber and O. Hovatta.  2006.  The derivation of clnical-grade human embryonic stem cell linesFEBS Letters.  580(12):2875-2878

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