Recommended Readings: Rachel Green, Ph.D. December 10

Special Seminar Series
Wednesday, December 10, 2014
4:00 p.m., Carson Family Auditorium (CRC)

Rachel Green, Ph.D.
Professor,
Department of Molecular Biology and Genetics,
Johns Hopkins University School of Medicine
Investigator,
Howard Hughes Medical Institute

Intimate Connections Between mRNA Decay and Translation

Recommended Readings

Empirical Articles

Djuranovic, S., Nahvi, A., & Green, R. (2012). miRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay. Science, 336(6078), 237–240. doi:10.1126/science.1215691

Koutmou, K. S., McDonald, M. E., Brunelle, J. L., & Green, R. (2014). RF3:GTP promotes rapid dissociation of the class 1 termination factor. RNA, 20(5), 609–620. doi:10.1261/rna.042523.113

Shoemaker, C. J., Eyler, D. E., & Green, R. (2010). Dom34:Hbs1 promotes subunit dissociation and peptidyl-tRNA drop-off to initiate no-go decay. Science, 330(6002), 369–372. doi:10.1126/science.1192430

Shoemaker, C. J., & Green, R. (2011). Kinetic analysis reveals the ordered coupling of translation termination and ribosome recycling in yeast. Proceedings of the National Academy of Sciences, 108(51), E1392–8. doi:10.1073/pnas.1113956108

Review Papers

Dever, T. E., & Green, R. (2012). The elongation, termination, and recycling phases of translation in eukaryotes. Cold Spring Harbor Perspectives in Biology, 4(7), a013706. doi:10.1101/cshperspect.a013706

Shoemaker, C. J., & Green, R. (2012). Translation drives mRNA quality control. Nature Structural & Molecular Biology, 19(6), 594–601. doi:10.1038/nsmb.2301

Recommended Readings: Susan Gottesman, Ph.D.

Friday Lecture Series

The Joshua Lederberg Memorial Lecture

Bacterial sRNA Regulatory Circuits and their On and Off Switches

Susan Gottesman, Ph.D., NIH Distinguished Investigator;

co-chief, Laboratory of Molecular Biology, National Cancer Institute

January 10, 2014

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Readings

De Lay, N., Schu, D. J., & Gottesman, S. (2013). Bacterial small RNA-based negative regulation: Hfq and its accomplices. Journal of Biological Chemistry, 288(12), 7996-8003

Gottesman, S. (2011). Microbiology: Dicing defence in bacteria. Nature, 471(7340), 588-589

Gottesman, S., & Storz, G. (2011). Bacterial small RNA regulators: Versatile roles and rapidly evolving variations. Cold Spring Harbor Perspectives in Biology, 3(12)

Mandin, P., & Gottesman, S. (2009). Regulating the regulator: An RNA decoy acts as an OFF switch for the regulation of an sRNA. Genes and Development, 23(17), 1981-1985

Soper, T., Mandin, P., Majdalani, N., Gottesman, S., & Woodson, S. A. (2010). Positive regulation by small RNAs and the role of hfq. Proceedings of the National Academy of Sciences of the United States of America, 107(21), 9602-9607