Friday Lecture Series
Genetic Protection from Diseases of Dietary Excess
Helen H. Hobbs, M.D.
Chief, Division of Medical Genetics, Professor of Internal Medicine and of Molecular Genetics, and Director, McDermott Center for Human Growth and Development; Investigator, Howard Hughes Medical Institute
The University of Texas Southwestern Medical Center at Dallas
Friday, February 27, 2009
3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)
Cohen, J., A. Pertsemlidis, I. K. Kotowski, R. Graham, C. K. Garcia, and H. H. Hobbs. 2005. Low LDL cholesterol in individuals of african descent resulting from frequent nonsense mutations in PCSK9. Nature Genetics. 37(2):161-165.
Cohen, J. C., E. Boerwinkle, T. H. Mosley Jr., and H. H. Hobbs. 2006. Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. New England Journal of Medicine. 354(12): 1264-1272.
Jain, T., R. Peshock, D. K. McGuire, D. Willett, Z. Yu, G. L. Vega, R. Guerra, H. H. Hobbs, and S. M. Grundy. 2004. African americans and caucasians have a similar prevalence of coronary calcium in the dallas heart study. Journal of the American College of Cardiology. 44(5):1011-1017.
Romeo, S., L. A. Pennacchio, Y. Fu, E. Boerwinkle, A. Tybjaerg-Hansen, H. H. Hobbs, and J. C. Cohen. 2007. Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL. Nature Genetics. 39(4):513-516.
Horton, J. D., J. C. Cohen, and H. H. Hobbs. 2007. Molecular biology of PCSK9: Its role in LDL metabolism. Trends in Biochemical Sciences. 32(2):71-77.
Rader, D. J., J. Cohen, and H. H. Hobbs. 2003. Monogenic hypercholesterolemia: New insights in pathogenesis and treatment. Journal of Clinical Investigation. 111(12):1795-1803.
Russell, D. W., V. Esser, and H. H. Hobbs. 1989. Molecular basis of familial hypercholesterolemia. Arteriosclerosis. 9(1 SUPPL.):I8-I13.
(Contact the Markus Library at ext. 8904 to request a copy of this article)