Recommended Readings: Beth Stevens, Ph.D. Friday May 4, 2018

Friday Lectures

Friday, May 4, 2018  3:45 p.m.

Caspary Auditorium

Beth Stevens Ph.D.

Associate Professor

Department of Neurology

Harvard Medical School – Boston Children’s Hospital

How the Immune System Sculpts Brain Circuitry

Recommended Readings:

Science News

Beth Stevens and Todd E. Golden. Deciphering neurodegeneration: Inflammation, immune response, and Alzheimer’s. (Webinar – February 7, 2018). Science

Empirical Articles

Shi, Qiaoqiao; Chowdhury, Saba; Ma, Rong; et al. (2017). Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice. SCIENCE TRANSLATIONAL MEDICINE. 9 (392)

Hong, Soyon; Beja-Glasser, Victoria F.; Nfonoyim, Bianca M.; et al. (2016). Complement and microglia mediate early synapse loss in Alzheimer mouse models. SCIENCE. 352 (6286): 712-716

Vasek, Michael J.; Garber, Charise; Dorsey, Denise; et al. (2016). A complement-microglial axis drives synapse loss during virus-induced memory impairment. NATURE. 534 (7608): 538-+

Sekar, Aswin; Bialas, Allison R.; de Rivera, Heather; et al. (2016). Schizophrenia risk from complex variation of complement component 4. NATURE. 530 (7589): 177-+

Schafer, Dorothy P.; Lehrman, Emily K.; Heller, Christopher T.; et al. (2014). An Engulfment Assay: A Protocol to Assess Interactions Between CNS Phagocytes and Neurons. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 88

Schafer, Dorothy P.; Lehrman, Emily K.; Kautzman, Amanda G.; et al. (2012). Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner. NEURON. 74 (4): 691-705

Review Paper

Salter, Michael W.; Stevens, Beth. (2017). Microglia emerge as central players in brain disease. NATURE MEDICINE. 23 (9): 1018-1027

Hong, Soyon; Dissing-Olesen, Lasse; Stevens, Beth. (2016). New insights on the role of microglia in synaptic pruning in health and disease. CURRENT OPINION IN NEUROBIOLOGY. 36: 128-134  

Bilimoria, Parizad M.; Stevens, Beth. (2015). Microglia function during brain development: New insights from animal models. BRAIN RESEARCH. 1617: 7-17  

Book Chapter

Stephan, Alexander H.; Barres, Ben A.; Stevens, Beth. (2012). The Complement System: An Unexpected Role in Synaptic Pruning During Development and Disease.  ANNUAL REVIEW OF NEUROSCIENCE. 35: 369-389