Recommended Readings: Jonas Frisén, M.D., Ph.D., October 16th

Friday Lecture Series
Friday, October 16, 2015
3:45 p.m., Caspary Auditorium

Jonas Frisén, M.D., Ph.D.
Tobias Foundation Professor of Stem Cell Research,
Department of Cell and Molecular Biology,
Karolinska Institutet, Stockholm, Sweden

Cellular Plasticity in the Intact and Injured Central Nervous System

Recommended Readings

Empirical Articles

Ernst, A., Alkass, K., Bernard, S., Salehpour, M., Perl, S., Tisdale, J., … & Frisén, J. (2014). Neurogenesis in the striatum of the adult human brain. Cell, 156(5), 1072-1083. doi: 10.1016/j.cell.2014.01.044

Magnusson, J. P., Göritz, C., Tatarishvili, J., Dias, D. O., Smith, E. M., Lindvall, O., … & Frisén, J. (2014). A latent neurogenic program in astrocytes regulated by Notch signaling in the mouse. Science, 346(6206), 237-241. doi: 10.1126/science.346.6206.237.

Sabelström, H., Stenudd, M., Réu, P., Dias, D. O., Elfineh, M., Zdunek, S., … & Frisén, J. (2013). Resident neural stem cells restrict tissue damage and neuronal loss after spinal cord injury in mice. Science, 342(6158), 637-640. doi: 10.1126/science.1242576

Review Paper

Bergmann, O., Spalding, K. L., & Frisén, J. (2015). Adult neurogenesis in humans. Cold Spring Harbor Perspectives in Biology, 7(7), a018994. doi: 10.1101/cshperspect.a018994

Recommended Readings: Susan L. Ackerman, Ph.D. May 2

Friday Lecture Series
Friday, April 25, 2014
3:45 p.m., Caspary Auditorium

Susan L. Ackerman, Ph.D.
Professor, The Jackson Laboratory
Investigator, Howard Hughes Medical Institute

Multicopy Genes Encoding Functional RNAs and Their Role in the CNS

Recommended Readings:

Empirical Articles

Jia, Y., Mu, J. C., & Ackerman, S. L. (2012). Mutation of a U2 snRNA gene causes global disruption of alternative splicing and neurodegeneration. Cell, 148(1-2), 296–308. doi:10.1016/j.cell.2011.11.057

Liu, Y., Zaun, H. C., Orlowski, J., & Ackerman, S. L. (2013). CHP1-mediated NHE1 biosynthetic maturation is required for Purkinje cell axon homeostasis. The Journal of Neuroscience, 33(31), 12656–12669. doi:10.1523/JNEUROSCI.0406-13.2013

Zhao, L., Longo-Guess, C., Harris, B. S., Lee, J.-W., & Ackerman, S. L. (2005). Protein accumulation and neurodegeneration in the woozy mutant mouse is caused by disruption of SIL1, a cochaperone of BiP. Nature Genetics, 37(9), 974–979. doi:10.1038/ng1620

Review Papers

Cooper, T. A, Wan, L., & Dreyfuss, G. (2009). RNA and disease. Cell, 136(4), 777–793. doi:10.1016/j.cell.2009.02.011

Lemmens, R., Moore, M. J., Al-Chalabi, A., Brown, R. H., & Robberecht, W. (2010). RNA metabolism and the pathogenesis of motor neuron diseases. Trends in Neurosciences, 33(5), 249–258. doi:10.1016/j.tins.2010.02.003