Recommended Readings: Michael W. Young, Ph.D., Monday October 8, 2018

Monday Lectures

Monday, October 8, 2018  4:00 p.m.

Carson Family Auditorium

Michael W. Young, Ph.D.

Richard and Jeanne Fisher Professor and Head

Laboratory of Genetics

The Rockefeller University

Genes Controlling Sleep and Circadian Rhythms

Recommended Readings:

Science News

Rosemary Braun. A Simple Blood Test Could Tell You the Time Inside Your Body. September 12, 2018. Discover Magazine

Empirical Articles

Young, Michael W. (2018). Time Travels: A 40-Year Journey from Drosophila’s Clock Mutants to Human Circadian Disorders (Nobel Lecture).  ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 57 (36): 11532-11539

Top, Deniz; Young, Michael W. (2018). Coordination between Differentially Regulated Circadian Clocks Generates Rhythmic Behavior. COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY. 10 (7)

Lin, Changfan; Top, Deniz; Manahan, Craig C.; et al. (2018). Circadian clock activity of cryptochrome relies on tryptophan-mediated photoreduction. PNAS. 115 (15): 3822-3827

Top, Deniz; O’Neil, Jenna L.; Merz, Gregory E.; et al. (2018). CK1/Doubletime activity delays transcription activation in the circadian clock. ELIFE. 7

Patke, Alina; Murphy, Patricia J.; Onat, Onur Emre; et al. (2017). Mutation of the Human Circadian Clock Gene CRY1 in Familial Delayed Sleep Phase Disorder. CELL.  169 (2): 203-215

Rogulja, Dragana; Young, Michael W. (2012). Control of Sleep by Cyclin A and Its Regulator. SCIENCE. 335 (6076): 1617-1621  

Zoltowski, Brian D.; Vaidya, Anand T.; Top, Deniz; et al. (2011). Structure of full-length Drosophila cryptochrome. NATURE. 480 (7377): 396-U156

Review Papers

Wijnen, Herman; Naef, Felix; Boothroyd, Catharine; et al. (2006). Control of daily transcript oscillations in Drosophila by light and the circadian clock. PLOS GENETICS. 2 (3): 326-343

Book Chapter

Axelrod, Sofia; Saez, Lino; Young, Michael W. (2015). Studying Circadian Rhythm and Sleep Using Genetic Screens in Drosophila. METHODS IN ENZIMOLOGY. 551: 3-27  

Crane, Brian R.; Young, Michael W. (2014). Interactive Features of Proteins Composing Eukaryotic Circadian Clocks. ANNUAL REVIEW OF BIOCHEMISTRY. 83: 191-219