Recommended Readings: Michael Rust, Ph.D., January 20, 2010

Monday Lecture Series

Lessons from the Cyanobacterial Circadian Clock

Michael Rust, Ph.D.,

Post Doctoral Fellow, FAS Center for Systems Biology

Harvard University

January 20, 2010

4:00p.m.-5:00 p.m.

Welch Hall, Level Two

Recommended Readings:

Rust MJ, Markson JS, Lane WS, et al.  2007.  Ordered phosphorylation governs oscillation of a three-protein circadian clock. SCIENCE 318(5851):809-812

Kreimer G.  2009.  The green algal eyespot apparatus: a primordial visual system and more? CURRENT GENETICS 55(1): 19-43

Hafner M, Koeppl H, Hasler M, et al.  2009.  ‘Glocal’ Robustness Analysis and Model Discrimination for Circadian Oscillators . PLOS COMPUTATIONAL BIOLOGY 5(10): Article Number: e1000534

Miyoshi F, Nakayama Y, Kaizu K, et al.  2007. A mathematical model for the Kai-protein-based chemical oscillator and clock gene expression rhythms in cyanobacteria.    JOURNAL OF BIOLOGICAL RHYTHMS 22(1): 69-80    Request article from Markus Library

Takigawa-Imamura H, Mochizuki A.  2006. Transcriptional autoregulation by phosphorylated and non-phosphorylated KaiC in cyanobacterial circadian rhythms.   JOURNAL OF THEORETICAL BIOLOGY 241(2):178-192    Request article from Markus Library.

Recommended Readings: Michael Rosbash, Ph. D. Oct. 9, 2009

Friday Lecture Series

Circadian Rhythms and the Transcriptional Feedback Loop

Michael Rosbach, Ph. D., professor and director

National Center for Behavioral Genomics, Brandeis University;

Howard Hughes Medical Institute, investigator

October 9, 2009

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Articles:

Kadener, S., J. S. Menet, K. Sugino, M. D. Horwich, U. Weissbein, P. Nawathean, V. V. Vagin, P. D. Zamore, S. B. Nelson, and M. Rosbash. 2009. A role for microRNAs in the drosophila circadian clock. Genes and Development 23, (18): 2179-219

Kadener, S., D. Stoleru, M. McDonald, P. Nawathean, and M. Rosbash. 2007. Clockwork orange is a transcriptional repressor and a new drosophila circadian pacemaker component. Genes and Development 21, (13): 1675-168

Rosbash, M. 2009. The implications of multiple circadian clock origins. PLoS Biology 7, (3): 0421-0425

Shang, Y., L. C. Griffith, and M. Rosbash. 2008. Light-arousal and circadian photoreception circuits intersect at the large PDF cells of the drosophila brain. Proceedings of the National Academy of Sciences of the United States of America 105, (50): 19587-19594

Stoleru, D., P. Nawathean, M. d. l. P. Fernández, J. S. Menet, M. F. Ceriani, and M. Rosbash. 2007. The drosophila circadian network is a seasonal timer. Cell 129, (1): 207-219

Plant Circadian Rhythms Impact Climate Change Studies

ScienceDaily (July 14, 2009) — The ability of plants to tell the time, a mechanism common to all living beings, enables them to survive, grow and reproduce. An international team has studied this circadian clock from a molecular viewpoint and has found an ecological implication: it makes climate change scenarios and CO2 level figures more accurate.

Resco et al. Ecological implications of plants’ ability to tell the time. Ecology Letters, 2009; 12 (6): 583 DOI: 10.1111/j.1461-0248.2009.01295.x