A New C. elegans Cell Death Program: Implications for
Neurodegeneration and Cancer
Shai Shaham, Ph.D.
Laboratory of Developmental Genetics
The Rockefeller University
4:00 p.m. Monday, March 26, 2012 Refreshments 3:45 Abby Lounge
Caspary Auditorium
Recommended readings:
Blum, E.S., Abraham, M.C., Yoshimura, S., Lu, Y., and S. Shaham. 2012. Control of nonapoptotic developmental cell death in Caeanorhabditis elegans by a polyglutamic-repeat protein. Science. 335(6071):970-973. DOI: 10.1126/science.1215156
McCall, K. 2010. Generic control of necrosis – another type of programmed cell death. Current Opinion in Cell Biology. 22(6):882-888. DOI: 10.1016/j.ceb.2010.09.002
Yuan, J. and G. Kroemer. 2010. Alternative cell death mechanisms in development and beyond. Genes & Development. 24(23):2592-2602. DOI: 10.1101/gad.1984410
Vlachos, M. and N. Tavernarakis. 2010. Non-apoptotic cell death in Caenorhabditis elegans. Developmental Dynamics. 239(5, S1):1337-1351. DOI: 10.1002/dvdy.22230
Miguel-Aliaga, I. and T. Stefan. 2009. Programmed cell death in the nervous system – a programmed cell fate? Current Opinion in Neurobiology. 19(2):127-133 DOI: 10.1016/j.conb.2009.04.002
Blum, E.S., M. Driscoll, and S. Shaham. 2008. Noncanonical cell death programs in the nematode Caenorhabditis elegans. Cell Death and Differeentiation. 15(7):1124-1131. DOI: 10.1038/cdd.2008.56
Abraham, M. C., L. Yun, and S. Shaham. 2007. A morphologically conserved nonapoptotic program promotes linker cell death in Caenorhabiditis elegans. Development Cell. 12(1):73-86. DOI: 10.1016/j.devcel.2006.11.012
