Recommended Readings: Sue Biggins, Ph.D., Friday May 5th, 2017

Friday Lectures

Friday, May 5th, 2017   3:45 p.m.

Caspary Auditorium

Sue Biggins, Ph.D.

Member and Associate Director

Division of Basic Sciences

Fred Hutchinson Cancer Research Center

Sensing Tension at Kinetochores

Recommended Readings:

https://www.ibiology.org/ibioseminars/chromosome-segregation.html 

Miller, Matthew P.; Asbury, Charles L.; Biggins, Sue (2016). A TOG Protein Confers Tension Sensitivity to Kinetochore-Microtubule Attachments. CELL. 165(6): 1428-1439

Musacchio, Andrea (2015). The Molecular Biology of Spindle Assembly Checkpoint Signaling Dynamics. CURRENT BIOLOGY.  25(20): R1002-R1018

Biggins, Sue (2015). Under tension: Kinetochores and Basic Research. GENETICS. 200(3): 681-682

London, Nitobe; Biggins, Sue (2014). Signalling dynamics in the spindle checkpoint response. NATURE REVIEWS MOLECULAR CELL BIOLOGY. 15 (11): 735-747

Sarangapani, Krishna K.; Duro, Eris; Deng, Yi; et al. (2014). Sister kinetochores are mechanically fused during meiosis I in yeast. SCIENCE. 346(6206): 248-251

Biggins, Sue (2013). The Composition, Functions, and Regulation of the Budding Yeast Kinetochore. GENETICS. 194(4): 817-846

Gonen, Shane; Akiyoshi, Bungo; Iadanza, Matthew G.; et al. (2012). The structure of purified kinetochores reveals multiple microtubule-attachment sites. NATURE STRUCTURAL & MOLECULAR BIOLOGY. 19( 9): 925-929

 

 

 

 
 
 

 

 

Recommended Readings: Hironori Funabiki, Ph.D.

Friday Lecture Series

Spindle or Envelope: Building Right on Chromosomes in Mitosis

Hironori Funabiki, Ph.D.,

associate professor, Laboratory of Chromosome and Cell Biology,

The Rockefeller University

October 4, 2013

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Readings

Carmena, M., Wheelock, M., Funabiki, H., & Earnshaw, W. C. (2012). The chromosomal passenger complex (CPC): From easy rider to the godfather of mitosis. Nature Reviews Molecular Cell Biology, 13(12), 789-803

Funabiki, H., & Murray, A. W. (2000). The xenopus chromokinesin xkid is essential for metaphase chromosome alignment and must be degraded to allow anaphase chromosome movement. Cell, 102(4), 411-424

Kelly, A. E., Ghenoiu, C., Xue, J. Z., Zierhut, C., Kimura, H., & Funabiki, H. (2010). Survivin reads phosphorylated histone H3 threonine 3 to activate the mitotic kinase aurora B. Science, 330(6001), 235-239

Rivera, T., Ghenoiu, C., Rodríguez-Corsino, M., Mochida, S., Funabiki, H., & Losada, A. (2012). Xenopus shugoshin 2 regulates the spindle assembly pathway mediated by the chromosomal passenger complex. EMBO Journal, 31(6), 1467-1479

Sampath, S. C., Ohi, R., Leismann, O., Salic, A., Pozniakovski, A., & Funabiki, H. (2004). The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly. Cell, 118(2), 187-202

Tseng, B. S., Tan, L., Kapoor, T. M., & Funabiki, H. (2010). Dual detection of chromosomes and microtubules by the chromosomal passenger complex drives spindle assembly. Developmental Cell, 18(6), 903-91