Special Seminar Series: Systems Biology

Scaling in Embryonic Development

Naama Barkai, Ph.D.

Associate Professor, Department of Molecular Genetics

Weizmann Institue of Science

Wednesday, January 14, 2009

4:00 p.m.-5:00 p.m. (Refreshments, 3:45 p.m.)

Second Floor, Welch Hall

Recommended Articles:

Ambrosio, A. L., V. F. Taelman, H. X. Lee, C. A. Metzinger, C. Coffinier, and E. M. De Robertis. 2008. Crossveinless-2 is a BMP feedback inhibitor that binds Chordin/BMP to regulate xenopus embryonic patterning. Developmental Cell. 15(2):248-260.

Lewis, J. 2008. From signals to patterns: Space, time, and mathematics in developmental biology. Science. 322(5900):399-403.

Ben-Zvi, D., B. -Z Shilo, A. Fainsod, and N. Barkai. 2008. Scaling of the BMP activation gradient in Xenopus embryos. Nature. 453(7199):1205-1211.

Cooke, J. 1981. Scale of body pattern adjusts to available cell number in amphibian embryos. Nature. 290(5809):775-778.

De Robertis, E. M., and Kuroda, H. Dorsal-ventral patterning and neural induction in Xenopus embryos. Annual Review of Cell and Developmental Biology. 20:285-308.

Dosch, R., and C. Niehrs. 2000. Requirement for anti-dorsalizing morphogenetic protein in organizer patterning. Mechanisms of Development. 90(2):195-203.

Ferguson, E. L. 1996. Conservation of dorsal ventral patterning in arthropods and chordates. Current Opinion in Genetics and Development. 6(4):424-431.

Khokha, M. K., J. Yeh, T. C. Grammer, and R. M. Harland. 2005. Depletion of three BMP antagonists from Spemann’s Organizer leads to a catastrophic loss of dorsal structures. Developmental Cell. 8(3):401-411.