Recommended Readings: Michael Elowitz, Ph.D.

Special Seminar Series: Systems Biology

Bacterial Differentiation and Development at the Single-cell Level

Michael Elowitz, Ph.D.

Assistant Professor of Biology and Applied Physics, and Bren Scholar

Division of Biology

California Institute of Technology

Investigator, HHMI

Wednesday, February 23, 2009

4:00 p.m.-5:00 p.m. (Refreshments, 3:45 p.m.)

Second Floor, Welch Hall

Recommended Articles:

Cai, L., C. K. Dalal, and M. B. Elowitz. 2008. Frequency-modulated nuclear localization bursts coordinate gene regulation. Nature. 455(7212):485-490.

Cox III, R. S., M. G. Surette, and M. B. Elowitz. 2007. Programming gene expression with combinatorial promoters. Molecular Systems Biology 3, art. no. 145 .

Dunlop, M. J., R. S. Cox III, J. H. Levine, R. M. Murray, and M. B. Elowitz. 2008. Regulatory activity revealed by dynamic correlations in gene expression noise. Nature Genetics. 40(12):1493-1498.

Elowitz, M. B., A. J. Levine, E. D. Siggia, and P. S. Swain. 2002. Stochastic gene expression in a single cell. Science. 297(5584):1183-1186.

Lahav, G., N. Rosenfeld, A. Sigal, N. Geva-Zatorsky, A. J. Levine, M. B. Elowitz, and U. Alon. 2004. Dynamics of the p53-Mdm2 feedback loop in individual cells. Nature Genetics. 36(2):147-150.

Rosenfeld, N., J. W. Young, U. Alon, P. S. Swain, and M. B. Elowitz. 2005. Gene regulation at the single-cell level. Science. 307(5717):1962-1965.

Sprinzak, D., and M. B. Elowitz. 2005. Reconstruction of genetic circuits. Nature. 438(7067):443-448.

Suel, G. M., J. Garcia-Ojalvo, L. M. Liberman, and M. B. Elowitz. 2006. An excitable gene regulatory circuit induces transient cellular differentiation. Nature. 440(7083):545-550.

Suel, G. M., R. P. Kulkarni, J. Dworkin, J. Garcia-Ojalvo, and M. B. Elowitz. 2007. Tunability and noise dependence in differentiation dynamics. Science. 315(5819):1716-1719.

Swain, P. S., M. B. Elowitz, and E. D. Siggia. 2002. Intrinsic and extrinsic contributions to stochasticity in gene expression. Proceedings of the National Academy of Sciences of the United States of America. 99(20):12795-12800.