Recommended Readings: Huda Zoghbi, M.D.

Friday Lecture Series

Neurodegenerative Diseases: The Dangers of Too Much Protein Stability

Huda Zoghbi, M.D., professor, Baylor College of Medicine;

investigator, Howard Hughes Medical Institute;

director, Jan and Dan Duncan Neurological Research Institute,

Texas Children’s Hospital

December 6, 2013

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Readings

Chahrour, M., & Zoghbi, H. Y. (2007). The story of rett syndrome: From clinic to neurobiology. Neuron, 56(3), 422-437

Fernandez-Funez, P., Nino-Rosales, M. L., De Gouyon, B., She, W. -., Luchak, J. M., Martinez, P., . . . Botas, J. (2000). Identification of genes that modify ataxin-1-induced neurodegeneration. Nature, 408(6808), 101-106

Jafar-Nejad, P., Ward, C. S., Richman, R., Orr, H. T., & Zoghbi, H. Y. (2011). Regional rescue of spinocerebellar ataxia type 1 phenotypes by 14-3-3ε haploinsufficiency in mice underscores complex pathogenicity in neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America, 108(5), 2142-2147

Lim, J., Hao, T., Shaw, C., Patel, A. J., Szabó, G., Rual, J. -., . . . Zoghbi, H. Y. (2006). A protein-protein interaction network for human inherited ataxias and disorders of purkinje cell degeneration. Cell, 125(4), 801-814

Riley, B. E., Zoghbi, H. Y., & Orr, H. T. (2005). SUMOylation of the polyglutamine repeat protein, ataxin-1, is dependent on a functional nuclear localization signal. Journal of Biological Chemistry, 280(23), 21942-21948

Zoghbi, H. Y., & Botas, J. (2002). Mouse and fly models of neurodegeneration. Trends in Genetics, 18(9), 463-471

Zoghbi, H. Y., & Warren, S. T. (2010). Neurogenetics: Advancing the “next-generation” of brain research. Neuron, 68(2), 165-173