Advance online publication in the January 10, 2010 issue of NATURE Structural and Molecular Biology presents breakthrough research on the mechanism of miRNA function. This research is being reported by the Stem Cell Research laboratories at the University of California, San Diego.
Friday Lecture Series
Richard M. Furlaud Distinguished Lecture
“Conserved Roles of Small RNAs in Genome Defense”
Gregory J. Hannon, Ph.D., professor and chair, program in genetics and bioinformatics, Cold Spring Harbor Laboratory; investigator, Howard Hughes Medical Institute
May 29, 2009
3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)
Malone, C. D., J. Brennecke, M. Dus, A. Stark, W. R. McCombie, R. Sachidanandam, and G. J. Hannon. 2009. Specialized piRNA pathways act in germline and somatic tissues of the drosophila ovary. Cell. 137:522–535.
Czech, B., C. D. Malone, R. Zhou, A. Stark, C. Schlingeheyde, M. Dus, N. Perrimon, et al. 2008. An endogenous small interfering RNA pathway in Drosophila. Nature. 453(7196):798-802.
Tam, O. H., A. A. Aravin, P. Stein, A. Girard, E. P. Murchison, S. Cheloufi, E. Hodges, et al. 2008. Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes. Nature. 453(7194):534-538.
Zhou, R., I. Hotta, A. M. Denli, P. Hong, N. Perrimon, and G. J. Hannon. 2008. Comparative analysis of argonaute-dependent small RNA pathways in Drosophila. Molecular Cell. 32(4):592-599.
Aravin, A. A., G. J. Hannon, and J. Brennecke. 2007. The piwi-piRNA pathway provides an adaptive defense in the transposon arms race. Science. 318(5851): 761-764.
Brennecke, J., C. D. Malone, A. A. Aravin, R. Sachidanandam, A. Stark, and G. J. Hannon. 2008. An epigenetic role for maternally inherited piRNAs in transposon silencing. Science. 322(5906): 1387-1392.
Girard, A., and G. J. Hannon. 2008. Conserved themes in small-RNA-mediated transposon control. Trends in Cell Biology. 18(3)136-148.
Kim, V. N., J. Han, and M. C. Siomi. 2009. Biogenesis of small RNAs in animals. Nature Reviews Molecular Cell Biology. 10(2):126-139.
Siomi, H., and M. C. Siomi. 2009. On the road to reading the RNA-interference code. Nature. 457(7228):396-404.
Malone, C. D., and G. J. Hannon. 2009. Small RNAs as guardians of the genome. Cell. 136(4):656-668.
Small RNA Sequencing Resolves Posttranscriptional
Thomas Tuschl Ph.D.
Howard Hughes Medical Institute
The Rockefeller University
4 p.m. (refreshments at 3:45)
Monday, December 15, 2008
Welch Hall Level Two
Zhao, Yi; Shunmin He,; et al. 2008. MicroRNA regulation of messenger-like noncoding RNAs: a network of mutual microRNA control Trends in Genetics 24(7): 323-327.
Orom, Ulf Andersson; Finn Cilius Nielsen. 2008. MicroRNA-10a binds the 5 ‘ UTR of ribosomal protein mRNAs and enhances their translation. Molecular Cell 30 (4):460-471.
Hudder, Alice; and Raymond F. Novak. 2008. miRNAs: Effectors of environmental influences on gene expression and disease. Toxicological Sciences 103(2): 228-240.
Lee, Ji Young; Soonhag Kim; et al. 2008. Development of a dual-luciferase reporter system for in vivo visualization of microRNA biogenesis and posttranscriptional regulation. Journal of Nuclear Medicine 49(2):285-294. Request article from Markus Library.
Ku, Gregory; and Michael T. McManus. 2008. Behind the scenes of a small RNA gene-silencing pathway. Human Gene Therapy 19(1):17-26. Request article from Markus Library.
Diederichs, Sven; and Daniel A.Haber. 2007. Dual role for argonautes in MicroRNA processing and Posttranscriptional regulation of MicroRNA expression. Cell 131(6): 1097-1108.
Zeng Yan; Heidi H. Sankala et al. 2008. Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies. Biochemical Journal 413(part 3): 429-436.
Ronemus, Michael; Matthew W. Vaughn; et al. 2006. MicroRNA-targeted and small interfering RNA-mediated mRNA degradation is regulated by Argonaute, Dicer, and RNA-dependent RNA polymerase in Arabidopsis. Plant Cell 18(7): 1559-1574.