Recommended Readings: Paul Bieniasz, Ph.D., December 14th

Monday Lecture Series
Monday, December 14, 2015
4:00 p.m., Carson Family Auditorium (CRC)

Paul Bieniasz, Ph.D.
Professor and Head,
Laboratory of Retrovirology,
The Rockefeller University and Aaron Diamond AIDS Research Center
Investigator, Howard Hughes Medical Institute

Retroviruses vs. Cells in Ancient and Modern Times

Recommended Reading

Empirical Articles

Busnadiego, I., Kane, M., Rihn, S. J., Preugschas, H. F., Hughes, J., Blanco-Melo, D., … & Wilson, S. J. (2014). Host and viral determinants of Mx2 antiretroviral activity. Journal of Virology, 88(14), 7738-7752. doi:10.1128/JVI.00214-14.

Hatziioannou, T., Del Prete, G. Q., Keele, B. F., Estes, J. D., McNatt, M. W., Bitzegeio, J., … & Bieniasz, P. D. (2014). HIV-1–induced AIDS in monkeys. Science, 344(6190), 1401-1405. doi:10.1126/science.1250761.

Kane, M., Yadav, S. S., Bitzegeio, J., Kutluay, S. B., Zang, T., Wilson, S. J., … & Bieniasz, P. D. (2013). MX2 is an interferon-induced inhibitor of HIV-1 infection. Nature, 502(7472), 563-566. doi:10.1038/nature12653.

Kutluay, S. B., Zang, T., Blanco-Melo, D., Powell, C., Jannain, D., Errando, M., & Bieniasz, P. D. (2014). Global changes in the RNA binding specificity of HIV-1 gag regulate virion genesis. Cell, 159(5), 1096-1109. doi:10.1016/j.cell.2014.09.057.

Rihn, S. J., Hughes, J., Wilson, S. J., & Bieniasz, P. D. (2015). Uneven genetic robustness of HIV-1 integrase. Journal of Virology, 89(1), 552-567. doi: 10.1128/JVI.02451-14.

Review Papers

Malim, M. H., & Bieniasz, P. D. (2012). HIV restriction factors and mechanisms of evasion. Cold Spring Harbor Perspectives in Medicine, 2(5), a006940.  doi:10.1101/cshperspect.a006940.

Recommended Readings: David D. Ho, M.D. April 21

Monday Lecture Series
Monday, April 21, 2014
4:00 p.m., Carson Family Auditorium

David D. Ho, M.D.
Irene Diamond Professor
Senior Physician
Scientific Director
Chief Executive Officer
Aaron Diamond AIDS Research Center
The Rockefeller University

Long-acting Antibodies and Drugs as Prophylactics in HIV Prevention

Recommended Readings:

Empirical Papers

Andrews, C. D., Spreen, W. R., Mohri, H., Moss, L., Ford, S., Gettie, A., … Ho, D. D. (2014). Long-acting integrase inhibitor protects macaques from intrarectal simian/human immunodeficiency virus. Science, 343(6175), 1151–1154. doi:10.1126/science.1248707

Baeten, J. M., Donnell, D., Ndase, P., Mugo, N. R., Campbell, J. D., Wangisi, J., … Celum, C. (2012). Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. The New England Journal of Medicine, 367(5), 399–410. doi:10.1056/NEJMoa1108524

Grant, R. M., Lama, J. R., Anderson, P. L., McMahan, V., Liu, A. Y., Vargas, L., … Glidden, D. V. (2010). Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. The New England Journal of Medicine, 363(27), 2587–2599. doi:10.1056/NEJMoa1011205

Song, R., Oren, D. a, Franco, D., Seaman, M. S., & Ho, D. D. (2013). Strategic addition of an N-linked glycan to a monoclonal antibody improves its HIV-1-neutralizing activity. Nature Biotechnology, 31(11), 1047–1052. doi:10.1038/nbt.2677

Review Articles

Spreen, W. R., Margolis, D. a, & Pottage, J. C. (2013). Long-acting injectable antiretrovirals for HIV treatment and prevention. Current Opinion in HIV and AIDS, 8(6), 565–571. doi:10.1097/COH.0000000000000002