Recommended Readings: Shai Shaham, Ph.D., Monday April 16, 2018

Monday Lectures

Monday, April 16, 2018  4:00 p.m.

Carson Family Auditorium

Shai Shaham, Ph.D.

Richard E. Salomon Family Professor and Head

Laboratory of Developmental Genetics

The Rockefeller University

Uncovering Cell Death Treasure Hiding in Plain Sight

Recommended Readings:

Science News

Brandon Specktor. See How a Single Cell Dies in Gory, Intricate Detail. (March 28, 2018). Live Science

Empirical Articles

Ghose P, Rashid A, Insley P, Trivedi M, Shah P, Singhal A, Lu Y, Bao Z, Shaham S. (2018). EFF-1 fusogen promotes phagosome sealing during cell process clearance in Caenorhabditis elegans. NATURE CELL BIOLOGY. 20 (4):393-399

Malin, Jennifer A.; Kinet, Maxime J.; Abraham, Mary C.; et al. (2016). Transcriptional control of non-apoptotic developmental cell death in C-elegans. CELL DEATH AND DIFFERENTIATION. 23 (12): 1985-1994

Schwendeman, Andrew R.; Shaham, Shai. (2016). A High-Throughput Small Molecule Screen for C-elegans Linker Cell Death Inhibitors. PLOS ONE. 11 (10) 

Kinet, Maxime J.; Malin, Jennifer A.; Abraham, Mary C.; et al. (2016). HSF-1 activates the ubiquitin proteasome system to promote non-apoptotic developmental cell death in C. elegans. ELIFE. 5

Blum, Elyse S.; Abraham, Mary C.; Yoshimura, Satoshi; et al. (2012). Control of Nonapoptotic Developmental Cell Death in Caenorhabditis elegans by a Polyglutamine-Repeat Protein. SCIENCE. 335 (6071): 970-973

Review Papers

Kutscher, Lena M.; Shaham, Shai (2017). Non-apoptotic cell death in animal development. CELL DEATH AND DIFFERENTIATION. 24 (8): 1326-1336

Blum, Elyse S.; Schwendeman, Andrew R.; Shaham, Shai. (2013). PolyQ disease: misfiring of a developmental cell death program? TRENDS IN CELL BIOLOGY. 23 (4): 168-174  

Book Chapters

Malin, Jennifer Zuckerman; Shaham, Shai. (2015). Cell Death in C. elegans Development. CURRENT TOPICS IN DEVELOPMENTAL BIOLOGY. 114: 1-42

Kinet, Maxime J.; Shaham, Shai. (2014). Noncanonical Cell Death in the Nematode Caenorhabditis elegans. METHODS IN ENZYMOLOGY. 545: 157-180


Recommended Readings: Victor Ambros, Ph.D.

Friday Lecture Series

microRNA Pathways in Animal Development

Joshua Lederberg Distinguished Lectureship in Molecular Genetics

Victor Ambros, Ph.D., Silverman Professor of Natural Science, co-director,

RNA Therapeutics Institute,

University of Massachusetts Medical School

February 3, 2012

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Readings:

Ambros, V. 2010. MicroRNAs: Genetically sensitized worms reveal new secrets. Current Biology 20, (14): R598-R600

Hammell, C. M., X. Karp, and V. Ambros. 2009. A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America 106, (44): 18668-18673

Hammell, C. M., I. Lubin, P. R. Boag, T. K. Blackwell, and V. Ambros. 2009. Nhl-2 modulates MicroRNA activity in caenorhabditis elegans. Cell 136, (5): 926-938

Hammell, M., D. Long, L. Zhang, A. Lee, C. S. Carmack, M. Han, Y. Ding, and V. Ambros. 2008. mirWIP: MicroRNA target prediction based on microRNA-containing ribonucleoprotein-enriched transcripts. Nature Methods 5, (9): 813-819

Miska, E. A., E. Alvarez-Saavedra, A. L. Abbott, N. C. Lau, A. B. Hellman, S. M. McGonagle, D. P. Bartel, V. R. Ambros, and H. R. Horvitz. 2007. Most caenorhabditis elegans microRNAs are individually not essential for development or viability. PLoS Genetics 3, (12): 2395-2403

Sokol, N. S., P. Xu, Y. -N Jan, and V. Ambros. 2008. Drosophila let-7 microRNA is required for remodeling of the neuromusculature during metamorphosis. Genes and Development 22, (12): 1591-1596