Recommended Readings: Brian Liau, Ph.D., February 3

Special Seminar
Wednesday, February 3, 2016
4:00 p.m., Carson Family Auditorium (CRC)

Brian Liau, Ph.D.
Jane Coffins Child Memorial Fund Postdoctoral Fellow,
Department of Pathology,
Massachusetts General Hospital,
Harvard Medical School

Chemical Epigenetics: Discovering Chromatin Mediated Mechanisms in Cancer Using Small Molecules

Recommended Reading

Flavahan, W. A., Drier, Y., Liau, B. B., Gillespie, S. M., Venteicher, A. S., Stemmer-Rachamimov, A. O., … & Bernstein, B. E. (2015). Insulator dysfunction and oncogene activation in IDH mutant gliomas. Nature. doi: 10.1038/nature16490

Pelish, H. E., Liau, B. B., Nitulescu, I. I., Tangpeerachaikul, A., Poss, Z. C., Da Silva, D. H., … & Du, K. (2015). Mediator kinase inhibition further activates super-enhancer-associated genes in AML. Nature, 526(7572), 273-276. doi: 10.1038/nature14904

van Galen, P., Viny, A. D., Ram, O., Ryan, R. J., Cotton, M. J., Donohue, L., … & Carroll, K. M. (2015). A Multiplexed system for quantitative comparisons of chromatin landscapes. Molecular Cell. doi: 10.1016/j.molcel.2015.11.003.

Recommended Readings: Andre Hoelz, Ph.D.; May 13, 2009

Special Seminar Series

            “Building the Gatekeeper of the Innermost Sanctuary of the Cell Piece by Piece”

Andre Hoelz, Ph.D.

Research Associate, Laboratory of Cell Biology

The Rockefeller University

Wednesday, May 13, 2009

4:00 p.m.-5:00 p.m. (Refreshments, 3:45 p.m.)

Second Floor, Welch Hall

Recommended Articles:

Debler, E. W., Y. Ma, H. -S Seo, K. -C Hsia, T. R. Noriega, G. Blobel, and A. Hoelz. 2008. A fence-like coat for the nuclear pore membrane. Molecular cell. 32(6):815-826.

Hoelz, A., and G. Blobel. 2004. Popping out of the nucleus. Nature. 432(7019):815-816.

Hsia, K. -C, P. Stavropoulos, G. Blobel, and A. Hoelz. 2007. Architecture of a coat for the nuclear pore membrane. Cell. 131(7):1313-1326.

Melcak, I., A. Hoelz, and G. Blobel. 2007. Structure of Nup58/45 suggests flexible nuclear pore diameter by intermolecular sliding. Science. 315(5819):1729-1732.

Napetschnig, J., G. Blobel, and A. Hoelz. 2007. Crystal structure of the N-terminal domain of the human protooncogene Nup214/CAN. Proceedings of the National Academy of Sciences of the United States of America. 104(6):1783-1788.

Stavropoulos, P., V. Nagy, G. Blobel, and A. Hoelz. 2008. Molecular basis for the autoregulation of the protein acetyl transferase Rtt109. Proceedings of the National Academy of Sciences of the United States of America. 105(34):12236-12241.