Recommended Readings: Nathaniel Heintz, Ph.D. Monday, Oct. 21

Understanding Neuronal Diversity: TRAP, Molecular Phenotyping and 5-hydroxymethylcytosine
Nathaniel Heintz, Ph.D.
Investigator, Howard Hughes Medical Institute
James and Marilyn Simons Professor
Laboratory of Molecular Biology
The Rockefeller University
4:00 p.m., Carson Family Auditorium

Recommended Readings

Review Paper

Branco, M. R., Ficz, G., & Reik, W. (2012). Uncovering the role of 5-hydroxymethylcytosine in the epigenome. Nature reviews. Genetics, 13(1), 7–13. doi:10.1038/nrg3080

Empirical Articles

Doyle, J. P., Dougherty, J. D., Heiman, M., Schmidt, E. F., Stevens, T. R., Ma, G., … Heintz, N. (2008). Application of a translational profiling approach for the comparative analysis of CNS cell types. Cell, 135(4), 749–762. doi:10.1016/j.cell.2008.10.029

Gong, S., Zheng, C., Doughty, M. L., Losos, K., Didkovsky, N., Schambra, U. B., … Heintz, N. (2003). A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature, 425(6961), 917–925. doi:10.1038/nature02033

Heiman, M., Schaefer, A., Gong, S., Peterson, J. D., Day, M., Ramsey, K. E., … Heintz, N. (2008). A translational profiling approach for the molecular characterization of CNS cell types. Cell, 135(4), 738–748. doi:10.1016/j.cell.2008.10.028

Heintz, N. (2004). Gene expression nervous system atlas (GENSAT). Nature neuroscience, 7(5), 483. doi:10.1038/nn0504-483

Kriaucionis, S., & Heintz, N. (2009). The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science, 324(5929), 929–30. doi:10.1126/science.1169786