Leptin, Behavior & Metabolism: Balancing the Energy Equation/in vivo/
Friday, March 2, 2007
Caspary Auditorium 3:45 p.m. – 5:15 p.m. Tea at 3:15 p.m. in the Abby Lounge
Recommended Review Article
Spiegelman, B. M. and Flier, J. S. (2001).Obesity and the regulation of energy balance. Cell 104:531-543.
Cohen, P. and Miyazaki, M. and Socci, N. D. and Hagge-Greenberg, A. and Liedtke, W. and Soukas, A. A. and Sharma, R. and Hudgins, L. C. and Ntambi, J. M. and Friedman, J. M. (2002).Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss. Science 297:240-243.
Cowley, M. A. and Smart, J. L. and Rubinstein, M. and Cordan, M. G. and Diano, S. and Horvath, T. L. and Cone, R. D. and Low, M. J. (2001).Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus. Nature 411:480-484.
Cowley, M. A. and Smith, R. G. and Diano, S. and Tschop, M. and Pronchuk, N. and Grove, K. L. and Strasburger, C. J. and Bidlingmaier, M. and Esterman, M. and Heiman, M. L. and Garcia-Segura, L. M. and Nillni, E. A. and Mendez, P. and Low, M. J. and Sotonyi, P. and Friedman, J. M. and Liu, H. Y. and Pinto, S. and Colmers, W. F. and Cone, R. D. and Horvath, T. L. (2003).The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis. Neuron 37:649-661.
Ellacott, K. L. J. and Cone, R. D. (2006).The role of the central melanocortin system in the regulation of food intake and energy homeostasis: lessons from mouse models. Philosophical Transactions of the Royal Society B-Biological Sciences 361:1265-1274.
Friedman, J. M. and Halaas, J. L. (1998).Leptin and the regulation of body weight in mammals. Nature 395:763-770.
Heisler, L. K. and Jobst, E. E. and Sutton, G. M. and Zhou, L. G. and Borok, E. and Thornton-Jones, Z. and Liu, H. Y. and Zigman, J. M. and Balthasar, N. and Kishi, T. and Lee, C. E. and Aschkenasi, C. J. and Zhang, C. Y. and Yu, J. and Boss, O. and Mountjoy, K. G. and Clifton, P. G. and Lowell, B. B. and Friedman, J. M. and Horvath, T. and Butler, A. A. and Elmquist, J. K. and Cowley, M. A. (2006).Serotonin reciprocally regulates melanocortin neurons to modulate food intake. Neuron 51:239-249.
Pinto, S. and Roseberry, A. G. and Liu, H. Y. and Diano, S. and Shanabrough, M. and Cai, X. L. and Friedman, J. M. and Horvath, T. L. (2004).Rapid rewiring of arcuate nucleus feeding circuits by leptin. Science 304:110-115.