Interchromosomal Interactions: Positive and Negative Regulators of Gene Expression
Monday, March 5, 2007
Welch Hall (2nd Floor)
3:45 p.m. Refreshments 4:00 p.m. Lecture
Recommended Review Article
Ansel, K. M. and Djuretic, I. and Tanasa, B. and Rao, A. (2006).Regulation of Th2 differentiation and Il4 locus accessibility. Annual Review of Immunology 24:607-656.
Cha, R. S. and Weiner, B. M. and Keeney, S. and Dekker, J. and Kleckner, N. (2000).Progression of meiotic DNA replication is modulated by interchromosomal interaction proteins, negatively by Spo11p and positively by Rec8p. Genes & Development 14:493-503.
Lee, G. R. and Kim, S. T. and Spilianakis, C. G. and Fields, P. E. and Flavell, R. A. (2006).T helper cell differentiation: Regulation by cis elements and epigenetics. Immunity 24:369-379.
Spilianakis, C. G. and Flavell, R. A. (2004).Long-range intrachromosomal interactions in the T helper type 2 cytokine locus. Nature Immunology 5:1017-1027.
Spilianakis, C. G. and Lalioti, M. D. and Town, T. and Lee, G. R. and Flavell, R. A. (2005).Interchromosomal associations between alternatively expressed loci. Nature 435:637-645.
Spilianakis, C. and Papamatheakis, J. and Kretsovali, A. (2000).Acetylation by PCAF enhances CIITA nuclear accumulation and transactivation of major histocompatibility complex class II genes. Molecular and Cellular Biology 20:8489-8498.
van Overveld, P. G. M. and Lemmers, Rjfl and Deidda, G. and Sandkuijl, L. and Padberg, G. W. and Frants, R. R. and van der Maarel, S. M. (2000).Interchromosomal repeat array interactions between chromosomes 4 and 10: a model for subtelomeric plasticity. Human Molecular Genetics 9:2879-2884.
Xu, N. and Tsai, C. L. and Lee, J. T. (2006).Transient homologous chromosome pairing marks the onset of X inactivation. Science 311:1149-1152.