Recommended Readings: Michael O’Donnell Ph.D. Monday December 12, 2016

Monday Lectures

 December 12, 2016

4:00 p.m.  Carson Family Auditorium  CRC

Michael O’Donnell  Ph.D.

HHMI Investigator, and Anthony and Judith Evnin Professor
Laboratory of DNA Replication

The Rockefeller University

The Eukaryotic Replisome

Recommended Readings:

O’Donnell, Mike; Li, Huilin   The Eukaryotic Replisome Goes Under the Microscope.  CURRENT BIOLOGY  26(6): R247-R256      MAR 21 2016

Yuan, Zuanning; Bai, Lin; Sun, Jingchuan; et al.   Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.  NATURE STRUCTURAL & MOLECULAR BIOLOGY   23(3): 217-224     MAR 2016

Sun, Jingchuan; Shi, Yi; Georgescu, Roxana E.; et al.   The architecture of a eukaryotic replisome.   NATURE STRUCTURAL & MOLECULAR BIOLOGY    22(12): 976-982 DEC 2015

Georgescu, Roxana E.; Schauer, Grant D.; Yao, Nina Y.; et al.  Reconstitution of a eukaryotic replisome reveals suppression mechanisms that define leading/lagging strand operation.      ELIFE    4: e04988     APR 14 2015

O’Donnell, Michael; Langston, Lance; Stillman, Bruce  Principles and Concepts of DNA Replication in Bacteria, Archaea, and Eukarya .   COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY    5(7): a010108