Related Readings – Dominique Frueh Ph.D.

Dynamic Communication in Nonribosomal Peptide Synthetases:

The T-TE Di-domain of Enterobactin Synthetase

Monday, March 31, 2008

Welch Hall    Markus Library Level Two     4 p.m.     Refreshments at 3:45 p.m.

Recommended Review Article:

Donadio, S.; Monciardini, P; and m. Sosio. (2007). Polyketide synthases and nonribosomal peptide synthetases: the emerging view from bacterial genomics.   Natural Products Reports. 24(5): 1073-1109

Related Articles:

Wilkinson, B. and J. Micklefield. (2007). Mining and engineering natural-product biosynthetic pathways.   Nature Chemical Biology   3(7):379-386

Tang, G.L.; YQ. Cheng; and B. Shen. (2007). Chain initiation in the leinamycin-producing hybrid nonribosomal peptide/polyketide synthetase from Streptomyces atroolivaceus S-140 – Discrete, monofunctional adenylation enzyme and peptidyl carrier protein that directly load D-Alanine.  Journal of Biological Chemistry  282(28):20273-20282

Zhou, Z.; Lai, J. R.; and Walsh, C.T. (2006). Interdomain communication between the thiolation and thioesterase domains of EntF explored by combinatorial mutagenesis and selection.  Chemistry & Biology   13(8):869-879

Doekel, S. (2000). Dipeptide formation on engineered hybrid peptide synthetases. Chemistry & Biology  7(6):373-384

Samuel, S.A. (2006) The thioesterase domain of the fengycin biosynthesis cluster: a structural base for the macrocyclization of a non-ribosomal lipopeptide. Journal of Molecular Biology  359:876-889

Shawreid, C.A. (1999). Assembly line enzymology by multimodular nonribosomal peptide synthetases: the thioesterase domain of E-coli EntF catalyzes both elongation and cyclolactonization. Chemistry & Biology 6(6):385-400