Friday Lecture Series

Jerry A. Weisbach Memorial Lecture

Signaling Networks That Regulate Synapse Development and Cognitive Function

Michael E. Greenberg, Ph.D., chair, department of neurobiology;

Nathan Marsh Pusey Professor of Neurobiology,

Harvard Medical School

 November 16, 2012

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Readings

Cohen, S., H. Gabel, M. Hemberg, A. N. Hutchinson, L. A. Sadacca, D. H. Ebert, D. A. Harmin, et al. 2011. Genome-Wide Activity-Dependent MeCP2 Phosphorylation Regulates Nervous System Development and Function. Neuron 72 (1): 72-85

Cohen, S. and M. E. Greenberg. 2008. Communication between the Synapse and the Nucleus in Neuronal Development, Plasticity, and Disease. Annual Review of Cell and Developmental Biology. Vol. 24

Greenberg, M. E., B. Xu, B. Lu, and B. L. Hempstead. 2009. New Insights in the Biology of BDNF Synthesis and Release: Implications in CNS Function. Journal of Neuroscience 29 (41): 12764-12767

Greer, P. L., R. Hanayama, B. L. Bloodgood, A. R. Mardinly, D. M. Lipton, S. W. Flavell, T. -K Kim, et al. 2010. The Angelman Syndrome Protein Ube3A Regulates Synapse Development by Ubiquitinating Arc. Cell 140 (5): 704-716

Margolis, S. S., J. Salogiannis, D. M. Lipton, C. Mandel-Brehm, Z. P. Wills, A. R. Mardinly, L. Hu, et al. 2010. EphB-Mediated Degradation of the RhoA GEF Ephexin5 Relieves a Developmental Brake on Excitatory Synapse Formation. Cell 143 (3): 442-455