Recommended Readings: Robert Lefkowitz, M.D.

Friday Lecture Series

Seven Transmembrane Receptors

Robert Lefkowitz, M.D., James B. Duke Professor of Medicine, Duke University

Medical Center,and investigator, Howard Hughes Medical Institute

October 12, 2012

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Readings

Chen, M., Philipp, M., Wang, J., Premont, R. T., Garrison, T. R., Caron, M. G., . . . Chen, W. (2009). G protein-coupled receptor kinases phosphorylate LRP6 in the wnt pathway. Journal of Biological Chemistry, 284(50), 35040-35048

Rajagopal, S., Ahn, S., Rominger, D. H., Gowen-MacDonald, W., Lam, C. M., DeWire, S. M., . . . Lefkowitz, R. J. (2011). Quantifying ligand bias at seven-transmembrane receptors. Molecular Pharmacology, 80(3), 367-377

Rajagopal, S., Kim, J., Ahn, S., Craig, S., Lam, C. M., Gerard, N. P., . . . Lefkowitz, R. J. (2010). β-Arrestin- but not G protein-mediated signaling by the “decoy” receptor CXCR7. Proceedings of the National Academy of Sciences of the United States of America, 107(2), 628-632

Rajagopal, S., Rajagopal, K., & Lefkowitz, R. J. (2010). Teaching old receptors new tricks: Biasing seven-transmembrane receptors. Nature Reviews Drug Discovery, 9(5), 373-386

Rockman, H. A., & Lefkowitz, R. J. (2011). Introduction to the series on novel aspects of cardiovascular g-protein-coupled receptor signaling. Circulation Research, 109(2), 202-204