New Mechanism for Dementia?

Hyperactive immune cells that engulf dying and injured cells before they have a chance to recover may contribute to neurodegeneration characteristic of some diseases, posing a previously unreported mechanism for dementia.  Biochemists of the University of California, San Francisco found preliminary evidence for a different pathway of neurodegeneration — one that involves the clearance of apoptotic cells by overly active phagocytic immune cells, such as macrophages, leading to widespread cell loss over time.  Read the full report of this research in PNAS.