Studying Yeast to Better Understand Male Infertility

ScienceDaily (Aug. 17, 2010) — Men and yeast have something in common: they use the same molecular process to ensure the integrity of their gene pool during reproduction. This is a recent finding by researchers from CNRS, Inserm and the Université Joseph Fourier in Grenoble, whose scientists are studying yeast in order to shed light on the numerous cases of male infertility related to the malfunction of this process during spermatogenesis.  

Over the last fifty years, male fertility has declined steadily. Men are thought to have lost half their spermatozoa in half a century, probably because of pollutants. But the fragility of the remaining spermatozoa is also responsible for this situation.   Read the research on the functional dynamics of histones in gametogenesis in Genes and Development.