Recommended Readings: Stephen J. Elledge Ph.D. Friday Oct 16, 2009

Friday Lecture Series

DNA Damage Response: Stopped for Repairs

Stephen J Elledge, Ph.D., HHMI

Geneticist, Department of Medicine, Brigham and Women’s Hospital

Gregor Mendel Professor of Genetics, Harvard Medical School

October 16, 2009

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Review Article:

Kerzendorfer C, O’Driscoll M.  2009. Human DNA damage response and repair deficiency syndromes: Linking genomic instability and cell cycle checkpoint proficiency. DNA REPAIR 8(9):1139-1152

Recommended Articles:

Chaurushiya MS, Weitzman MD  2009. Viral manipulation of DNA repair and cell cycle checkpoints. DNA REPAIR 8 (9): 1166-1176

Zhang NX, Kaur R, Akhter S, et al.  2009.  Cdc5L interacts with ATR and is required for the S-phase cell-cycle checkpoint. EMBO REPORTS 10( 9):1029-1035

Yan J, Jetten, AM .  2008.   RAP80 and RNF8, key players in the recruitment of repair proteins to DNA damage sites. CANCER LETTERS 271 (2): 179-190

Fu Y, Pastushok L, Xiao W.  2008.  DNA damage-induced gene expression in Saccharomyces cerevisiae. FEMS MICROBIOLOGY REVIEWS 32 ( 6): 908-926

Wang H, Elledge, SJ.  2002.  Genetic and physical interactions between DPB11 and DDC1 in the yeast DNA damage response pathway. GENETICS 160( 4): 1295-1304

Tibbetts RS, Cortez D, Brumbaugh KM, et al. 2000.   Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress. GENES & DEVELOPMENT 14( 23): 2989-3002

Zhou, BBS; Elledge, SJ.   2000.  The DNA damage response: putting checkpoints in perspective
NATURE 408 (6811): 433-439