Recommended Readings: Seth Darst, Ph.D. Monday November 6th, 2017

Monday Lectures

Monday, November 6, 2017  3:45 p.m.

Carson Family Auditorium

Seth Darst, Ph.D.

Jack Fishman Professor and Head

Laboratory of Molecular Biophysics

The Rockefeller University

Promoter Melting by Bacterial RNA Polymerase – One Step at a Time

Recommended Readings:

Feklistov, Andrey; Bae, Brian; Hauver, Jesse; et al. (2017). RNA polymerase motions during promoter melting. SCIENCE. 356 (6340): 863-866

Hubin, Elizabeth A.; Fay, Allison; Xu, Catherine; et al. (2017). Structure and function of the mycobacterial transcription initiation complex with the essential regulator RbpA. ELIFE. 6

Chen, James; Wassarman, Karen M.; Feng, Shili; et al. (2017). 6S RNA Mimics B-Form DNA to Regulate Escherichia coli RNA Polymerase. MOLECULAR CELL. 68 (2): 388-+

Bae, Brian; Feklistov, Andrey; Lass-Napiorkowska, Agnieszka; et al. (2015). Structure of a bacterial RNA polymerase holoenzyme open promoter complex. ELIFE. 4

Davis, Elizabeth; Chen, James; Leon, Katherine; et al. (2015). Mycobacterial RNA polymerase forms unstable open promoter complexes that are stabilized by CarD.  NUCLEIC ACIDS RESEARCH. 43 (1): 433-445

Chen, Jie; Darst, Seth A.; Thirumalai, D. (2010). Promoter melting triggered by bacterial RNA polymerase occurs in three steps. PNAS. 107 (28): 12523-12528