Recommended Readings: Max Cooper, M.D.

Friday Lecture Series

How Did Our Adaptive Immune System Evolve?

Max Cooper, M.D., professor, Emory Vaccine Center and Emory Center for AIDS Research, Emory University School of Medicine

January 31, 2014

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Readings

Alder, M. N., Rogozin, I. B., Iyer, L. M., Glazko, G. V., Cooper, M. D., & Pancer, Z. (2005). Immunology: Diversity and function of adaptive immune receptors in a jawless vertebrate. Science, 310(5756), 1970-1973

Cooper, M. D. (2010). A life of adventure in immunobiology. Annual Review of Immunology 28, 11-19

Cooper, M. D., & Herrin, B. R. (2010). How did our complex immune system evolve? Nature Reviews Immunology, 10(1), 2-3

Guo, P., Hirano, M., Herrin, B. R., Li, J., Yu, C., Sadlonova, A., & Cooper, M. D. (2009). Dual nature of the adaptive immune system in lampreys. Nature, 459(7248), 796-801

Hirano, M., Das, S., Guo, P., & Cooper, M. D. (2011). The evolution of adaptive immunity in vertebrates. Advances in Immunology 109, pp. 125-157

Pancer, Z., & Cooper, M. D. (2006). The evolution of adaptive immunity. Annual Review of Immunology 24 , pp. 497-518


Recommended Readings: Yuki Oka Ph.D. February 24

Monday, February 24, 2014
4:00 p.m., Carson Family Auditorium

Yuki Oka, Ph.D.
Postdoctoral Fellow
Department of Biochemistry and Molecular Biophysics
Columbia University

Neurobiology of Fluid Homeostasis: Peripheral and Central Regulation of Salt and Water Intake

Recommended Readings:

Empirical Articles

Chandrashekar, J., Kuhn, C., Oka, Y., Yarmolinsky, D. a, Hummler, E., Ryba, N. J. P., & Zuker, C. S. (2010). The cells and peripheral representation of sodium taste in mice. Nature, 464(7286), 297–301. doi:10.1038/nature08783

Oka, Y., Butnaru, M., von Buchholtz, L., Ryba, N. J. P., & Zuker, C. S. (2013). High salt recruits aversive taste pathways. Nature, 494(7438), 472–475. doi:10.1038/nature11905

Review Papers

Roper, S. D. (2013). Taste buds as peripheral chemosensory processors. Seminars in Cell & Developmental Biology, 24(1), 71–79. doi:10.1016/j.semcdb.2012.12.002

Sugita, M. (2006). Taste perception and coding in the periphery. Cellular and Molecular Life Sciences, 63(17), 2000–15. doi:10.1007/s00018-006-6100-0

Recommended Readings: Steve Lisberger, Ph.D.

Friday Lecture Series

What Happens in the Cerebellum while You Learn a Motor Skill

Steve Lisberger, Ph.D., George Barth Geller Professor and chair, department of neurobiology, Duke University School of Medicine;

investigator, Howard Hughes Medical Institute

January 24, 2014

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Readings

Li, J. X., & Lisberger, S. G. (2011). Learned timing of motor behavior in the smooth eye movement region of the frontal eye fields. Neuron, 69(1), 159-169

Li, J. X., Medina, J. F., Frank, L. M., & Lisberger, S. G. (2011). Acquisition of neural learning in cerebellum and cerebral cortex for smooth pursuit eye movements. Journal of Neuroscience, 31(36), 12716-12726

Medina, J. F., & Lisberger, S. G. (2009). Encoding and decoding of learned smooth-pursuit eye movements in the floccular complex of the monkey cerebellum. Journal of Neurophysiology, 102(4), 2039-2054

Medina, J. F., & Lisberger, S. G. (2008). Links from complex spikes to local plasticity and motor learning in the cerebellum of awake-behaving monkeys. Nature Neuroscience, 11(10), 1185-1192

Niu, Y. -., & Lisberger, S. G. (2011). Sensory versus motor loci for integration of multiple motion signals in smooth pursuit eye movements and human motion perception. Journal of Neurophysiology, 106(2), 741-753


RU Students Pick Their Favorite Books

MiddlesexAsterios PolypWhite TeethEnder's Game (The Ender Quintet, #1)Before Night Falls

We surveyed RU grad students for their favorite books and now offer them for everyone to enjoy. The full list of these 100 Student Picks and their availability can be found in Tri-Cat. Or, friend us on goodreads (username “Markus Library”).

You can browse the collection in our Cafe Lounge or find some of the titles on our library kindles, available for checkout at the service desk. For more information contact us at


Dandelion WineMrs. DallowayInvisible ManFire to FireThe Amazing Adventures of Kavalier & Clay

Recommended Readings: Poornima Parameswaran Ph.D. February 10

Monday, February 10, 2014
4:00 p.m., Carson Family Auditorium

Poornima Parameswaran, Ph.D.

Postdoctoral Research Fellow
School of Public Health
University of California, Berkeley

Virome & Immunome Diversity in Dengue & other Infectious Diseases

Recommended Readings:

Empirical Papers

Parameswaran, P., Charlebois, P., Tellez, Y., Nunez, A., Ryan, E. M., Malboeuf, C. M., … Henn, M. R. (2012). Genome-wide patterns of intrahuman dengue virus diversity reveal associations with viral phylogenetic clade and interhost diversity. Journal of Virology, 86(16), 8546–8558. doi:10.1128/JVI.00736-12

Parameswaran, P., Liu, Y., Roskin, K. M., Jackson, K. K. L., Dixit, V. P., Lee, J.-Y., … Fire, A. Z. (2013). Convergent antibody signatures in human dengue. Cell Host & Microbe, 13(6), 691–700. doi:10.1016/j.chom.2013.05.008

Parameswaran, P., Sklan, E., Wilkins, C., Burgon, T., Samuel, M. a, Lu, R., … Fire, A. Z. (2010). Six RNA viruses and forty-one hosts: viral small RNAs and modulation of small RNA repertoires in vertebrate and invertebrate systems. PLoS pathogens, 6(2), e1000764. doi:10.1371/journal.ppat.1000764

Review Articles

Fontana, J. M., Alexander, E., & Salvatore, M. (2012). Translational research in infectious disease: current paradigms and challenges ahead. Translational Research, 159(6), 430–453. doi:10.1016/j.trsl.2011.12.009

Wylie, K. M., Weinstock, G. M., & Storch, G. a. (2012). Emerging view of the human virome. Translational Research, 160(4), 283–290. doi:10.1016/j.trsl.2012.03.006

Recommended Readings: Edvard Moser, Ph.D., May-Britt Moser, Ph.D.

Friday Lecture Series

A Hexagonal Code for Space; Grid Cells, Place Cells and Memory

Edvard Moser, Ph.D., co-director, Kavli Institute for Systems Neuroscience; professor, Norwegian University of Science and Technology

May-Britt Moser, Ph.D., co-director, Kavli Institute for Systems Neuroscience; professor, Norwegian University of Science and Technology

January 17, 2014

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Readings

Boccara, C. N., Sargolini, F., Thoresen, V. H., Solstad, T., Witter, M. P., Moser, E. I., & Moser, M. -. (2010). Grid cells in pre-and parasubiculum. Nature Neuroscience, 13(8), 987-994

Bonnevie, T., Dunn, B., Fyhn, M., Hafting, T., Derdikman, D., Kubie, J. L., . . . Moser, M. -. (2013). Grid cells require excitatory drive from the hippocampus. Nature Neuroscience, 16(3), 309-317

Buzsáki, G., & Moser, E. I. (2013). Memory, navigation and theta rhythm in the hippocampal-entorhinal system. Nature Neuroscience, 16(2), 130-138

Giocomo, L., Moser, M. -., & Moser, E. (2011). Computational models of grid cells. Neuron, 71(4), 589-603

Giocomo, L. M., Hussaini, S. A., Zheng, F., Kandel, E. R., Moser, M. -., & Moser, E. I. (2011). Grid cells use HCN1 channels for spatial scaling. Cell, 147(5), 1159-1170

Jezek, K., Henriksen, E. J., Treves, A., Moser, E. I., & Moser, M. -. (2011). Theta-paced flickering between place-cell maps in the hippocampus. Nature, 478(7368), 246-249

Lu, L., Leutgeb, J. K., Tsao, A., Henriksen, E. J., Leutgeb, S., Barnes, C. A., . . . Moser, E. I. (2013). Impaired hippocampal rate coding after lesions of the lateral entorhinal cortex. Nature Neuroscience, 16(8), 1085-1093

Moser, E. I., & Moser, M. -. (2013). Grid cells and neural coding in high-end cortices. Neuron, 80(3), 765-774

Stensola, H., Stensola, T., Solstad, T., Froland, K., Moser, M. -., & Moser, E. I. (2012). The entorhinal grid map is discretized. Nature, 491(7427), 72-78


Recommended Readings: Andrew Kruse Ph.D. March 3

Monday, March 3, 2014
4:00 p.m., Carson Family Auditorium

Andrew Kruse, Ph.D.
Department of Molecular and Cellular Physiology
Stanford University School of Medicine

Structural insights into G protein-coupled receptor activation and allosteric modulation

Recommended Readings:

Empirical Papers

Haga, K., Kruse, A. C., Asada, H., Yurugi-Kobayashi, T., Shiroishi, M., Zhang, C., … Kobayashi, T. (2012). Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist. Nature, 482(7386), 547–551. doi:10.1038/nature10753

Kruse, A. C., Hu, J., Pan, A. C., Arlow, D. H., Rosenbaum, D. M., Rosemond, E., … Kobilka, B. K. (2012). Structure and dynamics of the M3 muscarinic acetylcholine receptor. Nature, 482(7386), 552–556. doi:10.1038/nature10867

Kruse, A. C., Ring, A. M., Manglik, A., Hu, J., Hu, K., Eitel, K., … Kobilka, B. K. (2013). Activation and allosteric modulation of a muscarinic acetylcholine receptor. Nature, 504(7478), 101–106. doi:10.1038/nature12735

Kruse, A. C., Weiss, D. R., Rossi, M., Hu, J., Hu, K., Eitel, K., … Shoichet, B. K. (2013). Muscarinic receptors as model targets and antitargets for structure-based ligand discovery. Molecular Pharmacology, 84(4), 528–540. doi:10.1124/mol.113.087551

Ring, A. M., Manglik, A., Kruse, A. C., Enos, M. D., Weis, W. I., Garcia, K. C., & Kobilka, B. K. (2013). Adrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobody. Nature, 502(7472), 575–579. doi:10.1038/nature12572

Review Articles

Kruse, A. C., Li, J., Hu, J., Kobilka, B. K., & Wess, J. (2013). Novel insights into M3 muscarinic acetylcholine receptor physiology and structure. Journal of Molecular Neuroscience. doi:10.1007/s12031-013-0127-0

Kruse, A. C., Manglik, A., Kobilka, B. K., & Weis, W. I. (2013). Applications of molecular replacement to G protein-coupled receptors. Acta Crystallographica. Section D, Biological Crystallography, 69(11), 2287–2292. doi:10.1107/S090744491301322X

Recommended Readings: Kristin Tessmar-Raible Ph.D. February 3

Monday, February 3, 2014
4:00 p.m., Carson Family Auditorium

Kristin Tessmar-Raible, Ph.D.
Junior Group Leader
Max F. Perutz Laboratories
University of Vienna

The Impact of Light on Nervous System Function

Recommended Readings:

Empirical Papers

Backfisch, B., Veedin Rajan, V. B., Fischer, R. M., Lohs, C., Arboleda, E., Tessmar-Raible, K., & Raible, F. (2013). Stable transgenesis in the marine annelid Platynereis dumerilii sheds new light on photoreceptor evolution. Proceedings of the National Academy of Sciences of the United States of America, 110(1), 193–198. doi:10.1073/pnas.1209657109

Fischer, R. M., Fontinha, B. M., Kirchmaier, S., Steger, J., Bloch, S., Inoue, D., … Tessmar-Raible, K. (2013). Co-expression of VAL- and TMT-opsins uncovers ancient photosensory interneurons and motorneurons in the vertebrate brain. PLoS Biology, 11(6), e1001585. doi:10.1371/journal.pbio.1001585

Zantke, J., Ishikawa-Fujiwara, T., Arboleda, E., Lohs, C., Schipany, K., Hallay, N., … Tessmar-Raible, K. (2013). Circadian and circalunar clock interactions in a marine annelid. Cell Reports, 5(1), 99–113. doi:10.1016/j.celrep.2013.08.031

Review Articles

Roenneberg, T., & Merrow, M. (2005). Circadian clocks – the fall and rise of physiology. Nature Reviews Molecular Cell Biology, 6(12), 965–971. doi:10.1038/nrm1766

Tessmar-Raible, K., Raible, F., & Arboleda, E. (2011). Another place, another timer: Marine species and the rhythms of life. BioEssays, 33(3), 165–172. doi:10.1002/bies.201000096

Recommended Readings: Susan Gottesman, Ph.D.

Friday Lecture Series

The Joshua Lederberg Memorial Lecture

Bacterial sRNA Regulatory Circuits and their On and Off Switches

Susan Gottesman, Ph.D., NIH Distinguished Investigator;

co-chief, Laboratory of Molecular Biology, National Cancer Institute

January 10, 2014

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Readings

De Lay, N., Schu, D. J., & Gottesman, S. (2013). Bacterial small RNA-based negative regulation: Hfq and its accomplices. Journal of Biological Chemistry, 288(12), 7996-8003

Gottesman, S. (2011). Microbiology: Dicing defence in bacteria. Nature, 471(7340), 588-589

Gottesman, S., & Storz, G. (2011). Bacterial small RNA regulators: Versatile roles and rapidly evolving variations. Cold Spring Harbor Perspectives in Biology, 3(12)

Mandin, P., & Gottesman, S. (2009). Regulating the regulator: An RNA decoy acts as an OFF switch for the regulation of an sRNA. Genes and Development, 23(17), 1981-1985

Soper, T., Mandin, P., Majdalani, N., Gottesman, S., & Woodson, S. A. (2010). Positive regulation by small RNAs and the role of hfq. Proceedings of the National Academy of Sciences of the United States of America, 107(21), 9602-9607


Recommended Readings: Martin Kampmann Ph.D. Monday, January 27

Monday, January 27, 2014
4:00 p.m., Carson Family Auditorium

Martin Kampmann, Ph.D.
Postdoctoral Scholar
University of San Francisco

Toward a Systematic Understanding of the Mammalian Proteostasis Network and its Therapeutic Potential

Recommended Readings:

Empirical Papers

Bassik, M. C., Kampmann, M., Lebbink, R. J., Wang, S., Hein, M. Y., Poser, I., … Weissman, J. S. (2013). A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility. Cell, 152(4), 909–922. doi:10.1016/j.cell.2013.01.030

Kampmann, M., Bassik, M. C., & Weissman, J. S. (2013). Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America, 110(25), E2317–2326. doi:10.1073/pnas.1307002110

Review Articles

Balch, W. E., Morimoto, R. I., Dillin, A., & Kelly, J. W. (2008). Adapting proteostasis for disease intervention. Science, 319(5865), 916–919. doi:10.1126/science.1141448

Hartl, F. U., Bracher, A., & Hayer-Hartl, M. (2011). Molecular chaperones in protein folding and proteostasis. Nature, 475(7356), 324–332. doi:10.1038/nature10317