Recommended Readings: Peter Palese, Ph.D.

Friday Lecture Series

Toward a Universal Influenza Virus Vaccine

Peter Palese, Ph.D., Horace W. Goldsmith Professor and chair,

department of microbiology,

Mount Sinai School of Medicine

 February 1, 2012

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Readings

Bouvier, N. M. and P. Palese. 2008. “The Biology of Influenza Viruses.” Vaccine 26 (SUPPL. 4): D49-D53

Hai, R., A. García-Sastre, D. E. Swayne, and P. Palese. 2011. “A Reassortment-Incompetent Live Attenuated Influenza Virus Vaccine for Protection Against Pandemic Virus Strains.” Journal of Virology 85 (14): 6832-6843

Kashyap, A. K., J. Steel, A. F. Oner, M. A. Dillon, R. E. Swale, K. M. Wall, K. J. Perry, et al. 2008. “Combinatorial Antibody Libraries from Survivors of the Turkish H5N1 Avian Influenza Outbreak Reveal Virus Neutralization Strategies.” Proceedings of the National Academy of Sciences of the United States of America 105 (16): 5986-5991

Medina, R. A., B. Manicassamy, S. Stertz, C. W. Seibert, R. Hai, R. B. Belshe, S. E. Frey, C. F. Basler, P. Palese, and A. Garcí-Sastre. 2010. “Pandemic 2009 H1N1 Vaccine Protects Against 1918 Spanish Influenza Virus.” Nature Communications 1 (3)

Wang, T. T. and P. Palese. 2011. “Catching a Moving Target.” Science 333 (6044): 834-835

Wang, T. T., G. S. Tan, R. Hai, N. Pica, L. Ngai, D. C. Ekiert, I. A. Wilson, A. García-Sastre, T. M. Moran, and P. Palese. 2010. “Vaccination with a Synthetic Peptide from the Influenza Virus Hemagglutinin Provides Protection Against Distinct Viral Subtypes.” Proceedings of the National Academy of Sciences of the United States of America 107 (44): 18979-18984


Recommended Readings: Beatrice H. Hahn, M.D.

Friday Lecture Series

Maclyn McCarty Memorial Lecture

Great Ape Reservoirs of Human AIDS and Malaria

Beatrice H. Hahn, M.D., professor, departments of medicine and microbiology,

University of Pennsylvania

 January 25, 2012

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Readings

Keele, B. F., J. H. Jones, K. A. Terio, J. D. Estes, R. S. Rudicell, M. L. Wilson, Y. Li, et al. 2009. “Increased Mortality and AIDS-Like Immunopathology in Wild Chimpanzees Infected with SIVcpz.” Nature 460 (7254): 515-519

Lee, H. Y., E. E. Giorgi, B. F. Keele, B. Gaschen, G. S. Athreya, J. F. Salazar-Gonzalez, K. T. Pham, et al. 2009. “Modeling Sequence Evolution in Acute HIV-1 Infection.” Journal of Theoretical Biology 261 (2): 341-360

Liu, J., B. F. Keele, H. Li, S. Keating, P. J. Norris, A. Carville, K. G. Mansfield, et al. 2010. “Low-Dose Mucosal Simian Immunodeficiency Virus Infection Restricts Early Replication Kinetics and Transmitted Virus Variants in Rhesus Monkeys.” Journal of Virology 84 (19): 10406-10412

Liu, W., Y. Li, G. H. Learn, R. S. Rudicell, J. D. Robertson, B. F. Keele, J. -B N. Ndjango, et al. 2010. “Origin of the Human Malaria Parasite Plasmodium Falciparum in Gorillas.” Nature 467 (7314): 420-425

Rayner, J. C., W. Liu, M. Peeters, P. M. Sharp, and B. H. Hahn. 2011. “A Plethora of Plasmodium Species in Wild Apes: A Source of Human Infection?” Trends in Parasitology 27 (5): 222-229

Sharp, P. M. and B. H. Hahn. 2010. “The Evolution of HIV-1 and the Origin of AIDS.” Philosophical Transactions of the Royal Society B: Biological Sciences 365 (1552): 2487-2494


Recommended Readings: Joseph Gleeson, M.D.

Friday Lecture Series

Developing Treatments for Pediatric Brain Diseases through Genomics

Joseph Gleeson, M.D., professor of neurosciences and pediatrics,

University of California, San Diego;

investigator, Howard Hughes Medical Institute

 January 11, 2012

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Readings

Dixon-Salazar, T. J., J. L. Silhavy, N. Udpa, J. Schroth, S. Bielas, A. E. Schaffer, J. Olvera, et al. 2012. “Exome Sequencing can Improve Diagnosis and Alter Patient Management.” Science Translational Medicine 4 (138)

Novarino, G., N. Akizu, and J. G. Gleeson. 2011. “Modeling Human Disease in Humans: The Ciliopathies.” Cell 147 (1): 70-79

Novarino, G., P. El-Fishawy, H. Kayserili, N. A. Meguid, E. M. Scott, J. Schroth, J. L. Silhavy, et al. 2012. “Mutations in BCKD-Kinase Lead to a Potentially Treatable Form of Autism with Epilepsy.” Science 338 (6105): 394-397

Parisi, M. A., C. L. Bennett, M. L. Eckert, W. B. Dobyns, J. G. Gleeson, D. W. W. Shaw, R. McDonald, A. Eddy, P. F. Chance, and I. A. Glass. 2004. “The NPHP1 Gene Deletion Associated with Juvenile Nephronophthisis is Present in a Subset of Individuals with Joubert Syndrome.” American Journal of Human Genetics 75 (1): 82-91

Yaari, R., I. A. Anselm, I. S. Szer, D. M. Malicki, M. P. Nespeca, and J. G. Gleeson. 2004. “Childhood Primary Angiitis of the Central Nervous System: Two Biopsy-Proven Cases.” Journal of Pediatrics 145 (5): 693-697